A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo +7 more
wiley +1 more source
The outcomes of concomitant off-pump coronary artery bypass grafting and pulmonary operations. [PDF]
Ateş MŞ +7 more
europepmc +1 more source
This work presents a continuous linear gradient catalyst layer design, a general strategy for improving membrane electrode assemblies across electrochemical devices. Fabricated via a dual‐nozzle spray coating method, the architecture controls the Pt/carbon ratio, ionomer content and ionomer type across the catalyst layer, enhancing proton conduction ...
Shangwei Zhou +15 more
wiley +1 more source
Off pump method of coronary artery bypass grafting enhances therapeutic efficacy and safety in elderly coronary heart disease patients. [PDF]
Li JD +5 more
europepmc +1 more source
Spectrally Tunable 2D Material‐Based Infrared Photodetectors for Intelligent Optoelectronics
Intelligent optoelectronics through spectral engineering of 2D material‐based infrared photodetectors. Abstract The evolution of intelligent optoelectronic systems is driven by artificial intelligence (AI). However, their practical realization hinges on the ability to dynamically capture and process optical signals across a broad infrared (IR) spectrum.
Junheon Ha +18 more
wiley +1 more source
The safety and efficacy of intravenous administration of tranexamic acid in off-pump coronary artery bypass grafting: a systematic review and meta-analysis. [PDF]
Zou ZY +4 more
europepmc +1 more source
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu +14 more
wiley +1 more source
Initial Outcomes from a Minimally Invasive Cardiac Surgery-Off-Pump Coronary Artery Bypass Grafting (MICS-OPCAB) Programme: A Case Series of the First 50 Patients Single-Centre Experience. [PDF]
AlMawajdeh O +3 more
europepmc +1 more source
This study advances our understanding of aortic valve stenosis by capturing spatially resolved chemical and structural changes at the nanoscale. The findings highlight the potential of combined Raman and electron microscopy for understanding calcification mechanisms across diverse tissue types.
Robin H. M. Van der Meijden +11 more
wiley +1 more source
Risk factors analysis and prediction model construction of low cardiac output syndrome after off-pump coronary artery bypass grafting. [PDF]
Guo P +6 more
europepmc +1 more source

