Results 61 to 70 of about 177,868 (333)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Incidence of postoperative atrial fibrillation in patients undergoing on-pump and off-pump coronary artery bypass grafting

open access: yesBrazilian Journal of Cardiovascular Surgery, 2015
Objective:To determine the incidence of postoperative atrial fibrillation in patients undergoing on-pump and off-pump coronary artery bypass grafting.Methods:A retrospective study with analysis of 230 medical records between January 2011 and October 2013
Milton Sérgio Bohatch Júnior   +5 more
doaj   +1 more source

A retrospective observational study of risk factors, angiographic patterns, short-term mortality and their correlations between on- pump and off- pump coronary artery bypass surgery

open access: yesHeart Vessels and Transplantation, 2023
Objective: The decision to perform on-pump or off-pump coronary bypass surgery (CABG) depends on various parameters such as myocardial contractility, thickness of the myocardium and overall surgeon preference.
C. Prabhakar Reddy   +1 more
doaj   +1 more source

A szívizom endogén adaptációja, szignál mechanizmusok, terápiás megfontolások: kísérletes és klinikai vizsgálatok = Endogenous adaptation of the myocardium, survival signals, therapeutic considerations: experimental and clinical investigations [PDF]

open access: yes, 2009
A pályázatban vizsgáltuk a miokardium endogén adaptációjával kiváltható protektív mechanizmusok molekuláris és celluláris folyamatait és klinikai lehetőségeit.
Gasz, Balázs   +5 more
core  

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Off‐pump coronary artery bypass surgery: physiology and anaesthetic management† [PDF]

open access: yes, 2017
Increasing interest is being shown in beating heart (off‐pump) coronary artery surgery (OPCAB) because, compared with operations performed with cardiopulmonary bypass, OPCAB surgery may be associated with decreased postoperative morbidity and reduced ...
Chassot, P.‐G   +4 more
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Comparison of Postoperative Anxiety, Depression, Somatization, and Somatosensory Perception Levels of Patients After Off-Pump and On-Pump Coronary Artery Bypass Graft Surgery

open access: yesİstanbul Medical Journal
Introduction: This study investigated the effect of coronary artery bypass grafting surgery performed using either the on-pump or off-pump technique on the levels of postoperative anxiety, depression, somatization, and somatosensory amplification in ...
İzzet Emir   +3 more
doaj   +1 more source

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