ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) improve outcomes in heart failure (HF) with preserved ejection fraction. Whether GLP‐1 RA prevent new‐onset HF in Type 2 diabetes or obesity requires further investigation. Methods We performed an updated meta‐analysis of randomized placebo‐controlled trials (RCT) of treatment ...
João Sérgio Neves +8 more
wiley +1 more source
Nomogram for predicting major bleeding after off-pump coronary artery bypass grafting
Objective The purpose of this investigation is to develop a novel nomogram for predicting major bleeding following off-pump coronary artery bypass grafting (CABG).
Jianqin Zhu +4 more
doaj +1 more source
Abstract Background Pharmacokinetic studies suggest that specific prostate cancer therapies may alter the metabolism of direct oral anticoagulants (DOACs), leading to elevated risks of thrombosis or bleeding. Methods To assess the risk of thrombosis or bleeding, population‐based, retrospective, parallel analyses were conducted in Ontario and Alberta ...
Tzu‐Fei Wang +10 more
wiley +1 more source
N-acetyl-B-D-glucosaminidase and inflammatory response after cardiopulmonary bypass [PDF]
OBJECTIVE: To determine the changes in activity of plasma N-acetyl-beta-D-glucosaminidase, a marker for inflammation as well as renal, pulmonary and cardiac damage and proinflammatory cytokines in patients undergoing coronary artery bypass grafting and ...
Iqbal, Perwaiz +5 more
core +1 more source
Commercial vascular grafts are made from ePTFE, a highly hydrophobic, foreign material that fails at a high rate in small‐diameter applications. Plasma polymer nanoparticles (PPN) are a versatile material functionalisation tool, used here to present fibrillin‐1 fragment PF8 on the graft surface.
Bob S. L. Lee +9 more
wiley +1 more source
ANUARIO 2012: CIRUGÍA CARDÍACA EN ADULTOS. LAS REVISTAS DE LAS SOCIEDADES NACIONALES PRESENTAN UNA SELECCIÓN DE LAS INVESTIGACIONES QUE HAN IMPULSADO AVANCES RECIENTES EN CARDIOLOGÍA CLÍNICA / Almanac 2012: Adult cardiac surgery. The National Society Journals present selected research that has driven recent advances in Clinical Cardiology [PDF]
Resumen Esta revisión abarca las más importantes publicaciones sobre cirugía cardíaca en adultos en los últimos años, incluida la base de la evidencia actual para la revascularización quirúrgica y el uso de la cirugía sin circulación extracorpórea, las ...
Ben Bridgewater
core
Longitudinal plasma interleukin‐6 and post‐stroke cognitive outcomes: The Stroke‐IMPaCT study
Abstract INTRODUCTION Inflammatory factors, particularly interleukin (IL)‐6, are implicated in post‐stroke cognitive decline, yet the association with longitudinal changes in these markers remains unclear. METHODS Plasma IL‐6 and other inflammatory markers were measured within 96 hours of ischemic stroke, and at 6–9 and 18–21 months, alongside ...
Natasha S. Carmichael +11 more
wiley +1 more source
Contemporary and Emerging Therapies in the Management of Refractory Angina: A Clinical Review
ABSTRACT Refractory angina (RA) represents a growing challenge in clinical cardiology, particularly in patients with obstructive coronary artery disease (CAD) who remain symptomatic despite optimal medical therapy and who are not candidates for revascularization.
Alex Angers‐Goulet +4 more
wiley +1 more source
Comparison of effectiveness of tranexamic acid and epsilon-amino-caproic-acid in decreasing postoperative bleeding in off-pump CABG surgeries: A prospective, randomized, double-blind study. [PDF]
Verma S +3 more
europepmc +1 more source
Transcatheter Left Ventricular Restoration in Ischemic Heart Failure and Dilated Cardiomyopathy
ABSTRACT Ischemic heart disease is the leading global cause of death and frequently progresses to ischemic heart failure (IHF) after myocardial infarction through adverse left ventricular (LV)remodeling. Surgical LV restoration improves ventricular geometry and function but is limited by invasiveness and inconsistent outcomes.
Muhammad Mohid Haroon +19 more
wiley +1 more source

