Results 161 to 170 of about 18,568 (294)

Computational analysis to assess hemodynamic forces in descending thoracic aortic aneurysms

The Journal of Physiology, EarlyView.
Abstract figure legend Left: Pre‐processing. First, we perform the segmentation of the Computer Tomography angiorgraphy (angio‐CT) scans of a healthy patient, obtaining the surface of a healthy thoracic aorta with a Type III aortic arch. Then, we build nine ideal configurations with Descending Thoracic Aortic Aneurysm (DTAA), varying the aortic arch ...
Francesca Duca, Daniele Bissacco, Luca Crugnola, Chiara Faitini, Maurizio Domanin, Francesco Migliavacca, Santi Trimarchi, Christian Vergara   +7 more
wiley   +1 more source

Simultaneous Surgical Treatment of Non-small Cell Lung Cancer and Off-pump Coronary Artery bypass Grafting

Chinese Journal of Lung Cancer, 2009
Background and objective Patients with resectable lung cancer and unstable coronary heart disease are at high risks of postoperative death or severe cardioovascular complications. They always pose a therapeutic challenge for thoracic surgeons. The aim of
Yi ZHANG, Xiang WEI, Tiecheng PAN
doaj  

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury

The Journal of Physiology, EarlyView.
Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich, Ulas Ozkurede, Shanmugasundaram Pakkiriswami, Ryan Gemilere, Samira M. Azarin, Julia C. Liu   +5 more
wiley   +1 more source

Metabolite‐sensitive cross‐bridge models of human atria reveal the impact of diabetes on muscle mechanoenergetics

The Journal of Physiology, EarlyView.
Abstract figure legend In this study, we used mathematical modelling to explore the effect of diabetes on muscle mechanoenergetics. Our parameterisation of cross‐bridge models using data from non‐diabetic and diabetic human atrial tissues revealed lower values for cross‐bridge stiffness, detachment rates, attachment rates and lower ATP sensitivity in ...
Julia H. Musgrave, June‐Chiew Han, Marie‐Louise Ward, Andrew J. Taberner, Kenneth Tran   +4 more
wiley   +1 more source

Isolated iron deficiency in off-pump coronary artery bypass grafting. [PDF]

Korean J Anesthesiol
Ju JW.
europepmc   +1 more source

The influence of delayed ventricular activation on cardiac repolarization: Insights from electrocardiographic imaging

The Journal of Physiology, EarlyView.
Abstract figure legend This study examines the relationships between activation and repolarization times in epicardial reconstructed unipolar electrograms derived from ECG‐imaging in patients with normal and delayed ventricular activation. In patients with a narrow QRS‐complex, ECG‐imaging reveals significant variability in the activation ...
Karin C. Smits, Ted E.M. Lempers, Marc Strik, Job Stoks, Roel Meiburg, Matthijs J.M. Cluitmans, Paul G.A. Volders, Kevin Vernooy, Frits W. Prinzen, Uyên Châu Nguyên   +9 more
wiley   +1 more source

Complex composite conduits for anaortic off-pump coronary artery bypass grafting: Lambda and pi grafts. [PDF]

JTCVS Tech
Hynes CF, Puskas JD.
europepmc   +1 more source

Intravenous Tolvaptan Sodium Phosphate Can Fail to Improve Fluid Overload Due to Heart Failure in Patients With Chronic Kidney Disease: A Case Report

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Tolvaptan is widely used as an adjunct oral diuretic to loop and thiazide diuretics for the management of fluid overload in patients with congestive heart failure. Recently, tolvaptan sodium phosphate (TSP), a water‐soluble prodrug of tolvaptan, was developed for intravenous administration and has demonstrated efficacy and safety in clinical ...
Takaya Uno, Ichiro Nakakura, Akari Ikeda, Atsuki Hosoda, Yutaro Mukai, Kaori Yamanishi, Naohiro Ohara, Kaori Imanishi, Yoshiko Une, Satoshi Yokoyama, Kouichi Hosomi   +10 more
wiley   +1 more source

Machine learning-based prediction of 1-year mortality risk after off-pump coronary artery bypass grafting. [PDF]

J Thorac Dis
Ma Y, Shi Y, Yin R.
europepmc   +1 more source