Results 201 to 210 of about 18,568 (294)

TET3‐Mediated m5C Modification of CCAT2 Accelerates Cardiac Microvascular Endothelial Cell Damage in Acute Coronary Syndrome

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 42, Issue 5, May 2026.
ABSTRACT Acute coronary syndrome (ACS) is a clinical syndrome involving myocardial ischemia. This study aimed to elucidate the mechanism of TET3 in ACS‐induced CMEC damage, thereby identifying a new target for ACS treatment. The expression of TET3 in ACS patients and healthy subjects was analyzed.
Jun‐Cheng Liu   +5 more
wiley   +1 more source

mRNA Lipid Nanoparticles for Cell Engineering in Vivo and in Vitro: Current Applications and Future Directions

open access: yesMedComm, Volume 7, Issue 5, May 2026.
Schematic diagram of mRNA‐lipid nanoparticles (mRNA‐LNP) and its functional mechanisms, applications, and challenges in cell engineering. This figure details the structural composition of mRNA‐LNPs and the delivery strategy, highlighting three core challenges.
Lina Li   +9 more
wiley   +1 more source

Risk of Safety Events in Vitiligo Patients: A Retrospective Real‐World Data Study in the US

open access: yesThe Journal of Dermatology, Volume 53, Issue 5, Page 758-773, May 2026.
ABSTRACT Vitiligo is a chronic autoimmune depigmenting disease characterized by loss of pigment in the skin, hair, or both. As treatment options evolve, particularly with the emergence of oral Janus kinase inhibitors and dual Janus kinase 3/tyrosine kinase expressed in hepatocellular carcinoma family kinase inhibitor, it is essential to assess ...
Kennedy Cook   +11 more
wiley   +1 more source

Drainage of Pleural Effusion in the Intensive Care Unit (DOPE‐ICU) Feasibility Trial—Protocol and Statistical Analysis Plan

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 5, May 2026.
ABSTRACT Pleural effusions are common in adult intensive care unit (ICU) patients with respiratory failure. Ultrasonography‐guided therapeutic pleural drainage is widely used and associated with improved oxygenation and ventilatory parameters, but no randomised clinical trial data exist.
Marie Schjødt Worm   +6 more
wiley   +1 more source

Early Prediction of Neurological Outcome After Cardiac Arrest‐Rationale and Design of the Prospective International Observational EARLY‐NEURO, a STEPCARE Substudy

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 5, May 2026.
ABSTRACT Background Guidelines discourage prediction of neurological outcome in comatose patients within the first 72 h after cardiac arrest. Increasing evidence suggests that patients with the most severe brain injury and those with no or minimal brain injury may be identified before 72 h using novel methods.
Marion Moseby‐Knappe   +48 more
wiley   +1 more source

On-pump versus off-pump coronary artery bypass grafting for left main coronary artery disease: long-term outcomes. [PDF]

open access: yesJ Thorac Dis
Kim TO   +9 more
europepmc   +1 more source

Estimating Vascular Age to Evaluate the Association Between Aging and Cardiovascular Disease

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
The normalized cardiovascular age acceleration (NCAA) index is estimated using the Klemera‐Doubal method (KDM) based on annual physical examination records at Tongji Hospital in Wuhan, China. Vascular function‐based (basic) NCAA shows different associations with cardiometabolic risk factors by age and sex.
Yueqi Lu   +10 more
wiley   +1 more source

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