Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Targeting Investment in On-farm Surface Water Storage for Groundwater Conservation. [PDF]
Kovacs KF.
europepmc +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Efficiency Evaluation of Sampling Density for Indoor Building LiDAR Point-Cloud Segmentation. [PDF]
Zou Y, Chen W, Liang T, Xiong B.
europepmc +1 more source
Leveraging Digital Technologies to Enhance Mass Customization in Off-Site Construction
J. M. S. M. Pieris +2 more
openalex +1 more source
Stochastic-based noise exposure assessment in modular and off-site construction
Sanam Dabirian +2 more
openalex +2 more sources
Model Stormwater Standards for Coastal Watershed Communities [PDF]
Rockingham Planning Commission +1 more
core +1 more source
NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source
Corrigendum "Hybrid optimization method for optimal site selection and sizing of a hybrid photovoltaic water pumping/diesel/battery system" [Heliyon Volume 11, Issue 1, January 2025, Article e40692]. [PDF]
Maleki A, Heydari F, Moghadam AJ.
europepmc +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source

