Results 21 to 30 of about 191,978 (238)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Barriers and Challenges for Offsite Construction in UK Housing Sector [PDF]

open access: yes, 2017
Offsite construction (OSC) has been presented by researchers and practitioners all over the world as an efficient and effective way of delivering buildings. The benefits regarding time, cost and quality are well-documented.
Arif, Mohammed   +4 more
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Rapid manufacturing as a tool for agile manufacturing: applications and implementation perspectives [PDF]

open access: yes, 2006
Manufacturing engineers and technologists around the globe are already well familiar with manufacturing methodologies and systems developments in the last part of the twentieth century.
Bateman, RJ, Cheng, K
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Tracking Chart 2008 H&M in China (Factory 5, December) [PDF]

open access: yes, 2008
The FLA uses Tracking Charts to provide the public with information about the compliance situation of individual factories - the specific problems that were found by monitors and the action taken by participating companies in response to the findings ...
Fair Labor Association
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Improving the mechanical recycling and reuse of mixed plastics and polymer composites [PDF]

open access: yes, 2009
This is a post-print version of the chapter.In this chapter we will explore the possibilities and viability of commercially recycling and reusing of composites and mixed polymer based waste that is difficult and expensive to separate into individual ...
Tarverdi, K
core  

Towards the Design of Heuristics by Means of Self-Assembly [PDF]

open access: yes, 2010
The current investigations on hyper-heuristics design have sprung up in two different flavours: heuristics that choose heuristics and heuristics that generate heuristics.
Dario Landa-Silva   +5 more
core   +5 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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