Results 131 to 140 of about 3,607,027 (253)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Introduction.

, 1996
Offer, Avner
core   +1 more source

Localizing Prevention: Insights from Youth Voices on Culturally Grounded Substance Use Prevention Implementation in Windward O'ahu. [PDF]

Transl Issues Psychol Sci
Rapadas CC, Goshgarian-Miller S, Yamane RM, Carreira Ching DL, Primack Z, Yoshizumi-Kim N, Palafu T, Chin SK, Almanza P, Park AL, Okamoto SK, Okamura KH.   +11 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Deckungsbeitragstabellen in der Waldbewertung

, 2009
Staupendahl, K., Offer, A.
core   +2 more sources

Global Perspectives on Radiotherapy Utilization for Pancreatic Ductal Adenocarcinoma. [PDF]

J Gastrointest Cancer
Reames BN, Miller ED, Zhou Z, Narang A, Quinn PL, White B, Gogineni E, Ejaz A.   +7 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

No Surprises Act Independent Dispute Resolution: A Five-Gate Evidentiary Framework for Evaluating Reform Claims. [PDF]

Cureus
Klapper AM, Dardano AN, Risin M, Florio T, Denavea M.   +4 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Soziale Sicherheit im supranationalen Kontext: Europäische Integration und die Zukunft des "Europäischen Sozialmodells"

, 2005
Offer, Claus
core   +1 more source