Results 141 to 150 of about 5,968,774 (351)

Effects of louvers shading devices on visual comfort and energy demand of an office building. A case of study

open access: yes, 2017
Daylight contributes to indoor visual comfort, enhances user satisfaction and productivity, and explains partially that, in office buildings, the use of glass in the facades has increased in the last few years, even in places where solar gains through ...
Francisco Fernández Hernández   +4 more
semanticscholar   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Unimplemented Project: Konya Telegraph and Post Office Building

open access: yesArt-Sanat
An institution that underwent radical change during the Tanzimat era was the postal organization. Following the reform process that started during the reign of Mahmud II, the modernization process of the postal services accelerated in the late 19th ...
Emre Kolay
doaj   +1 more source

Energy and thermal modelling of an office building to develop an artificial neural networks model. [PDF]

open access: yesSci Rep, 2022
Santos-Herrero JM   +3 more
europepmc   +1 more source

Is There a Term Structure? Empirical Evidence from Shanghai Office Rental Market [PDF]

open access: yes
This paper mainly conducts an empirical study of the term structure of the Shanghai office rental market. Based on 555 executed contracts in the Shanghai office rental market from 2005 to 2008, the building quality and micro location are controlled ...
Fang Fang, Lu Ruichang
core  

Influence of filtration on I/O particle concentration ratios at urban office buildings [PDF]

open access: yes, 2012
Epidemiological research has consistently shown an association between fine and ultrafine particle concentrations, and increases in both respiratory and cardiovascular morbidity and mortality.
He, Congrong   +3 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

A prototype office building [PDF]

open access: yes, 1956
Thesis (M.Arch.) Massachusetts Institute of Technology. Dept.
Zemaitis, Algimantas
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

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