Results 151 to 160 of about 5,968,774 (351)

Direct Radiation Model of Louver Shading in Office Building Shade Based on Network Optimization Method. [PDF]

Comput Intell Neurosci, 2022
He D, Jianguo C, Xing H.
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Evaluating SARS-CoV-2 airborne quanta transmission and exposure risk in a mechanically ventilated multizone office building. [PDF]

Build Environ, 2022
Yan S, Wang LL, Birnkrant MJ, Zhai J, Miller SL.   +4 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Fostering Cultures of Sustainability in a Multi-Unit Office Building: A Theory of Change. [PDF]

Front Psychol, 2021
Dreyer BC, Riemer M, Spadafore B, Marcus J, Fernandes D, Taylor A, Whitney S, Geobey S, Dennett A.   +8 more
europepmc   +1 more source

Walmart\u27s Sustainability Journey: Andy Ruben and the Design of Organizaional Structures and Systems (A) [PDF]

, 2012
The case “Andy Ruben and the Design of Strategic Goals and Processes” flows from the previous discussion, by moving from the development of an ambitious vision to the challenges of adopting strategic policies and processes to reach those aspirations in ...
Lambdin, Laura, Spicer, Andrew
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Detailed operational building data for six office rooms in Denmark: Occupancy, indoor environment, heating, ventilation, lighting and room control monitoring with sub-hourly temporal resolution

Data in Brief
The operational building data presented in this paper has been collected from six office rooms located in an office building (research and educational purposes) located on the main campus of Aalborg University in Denmark.
Simon Pommerencke Melgaard, Hicham Johra, Victor Ørsøe Nyborg, Anna Marszal-Pomianowska, Rasmus Lund Jensen, Christos Kantas, Olena Kalyanova Larsen, Yue Hu, Kirstine Meyer Frandsen, Tine Steen Larsen, Kjeld Svidt, Kamilla Heimar Andersen, Daniel Leiria, Markus Schaffer, Martin Frandsen, Martin Veit, Lene Faber Ussing, Søren Munch Lindhard, Michal Zbigniew Pomianowski, Lasse Rohde, Anders Rhiger Hansen, Per Kvols Heiselberg   +21 more
doaj   +1 more source