Results 191 to 200 of about 17,119,270 (336)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Per- and Polyfluoroalkyl Substances During Pregnancy and Gestational Diabetes: The Environmental Influences on Child Health Outcomes (ECHO) Cohort. [PDF]

Diabetes Care
Starling AP, Burjak M, Nzegwu AW, Xun X, Adgate JL, Barrett ES, Bennett DH, Chatzi L, Colicino E, Dabelea D, Dunlop AL, Eick SM, Farzan SF, Ferrara A, Fleisch AF, Geiger SD, Hedderson MM, Kahn LG, Karagas MR, Kelly RS, Liang D, Lin PI, O'Connor TG, Padula AM, Peterson AK, Romano ME, Sathyanarayana S, Zhu Y, Valvi D, ECHO Cohort Consortium* .   +29 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Correction: Strive for excellence: unboxing the antecedents of art design students' creativity in the learning process in China. [PDF]

Front Psychol
Jianhao J, Ng V, Hin LC, Mohamed MR, Hossain MS.   +4 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

A Cost Analysis of Carpal Tunnel Procedures Performed in an Office Procedure Room Versus a Hospital Operating Room in a Rural Midwest Health System. [PDF]

Plast Surg (Oakv)
Hurley LJ, Hardie KA, Van Demark RE.
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Correction: How would Marie Kondo design a protocol? In favor of subtractive change in clinical trials. [PDF]

Front Med (Lausanne)
Bender Ignacio R, Rowan K, Cook D.
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Design for office

The Japanese journal of ergonomics, 1990
openaire   +2 more sources