Results 61 to 70 of about 660,630 (306)
Experimental verification of a tuned mass damper system with two‐phase support mechanism
Japan Architectural Review, 2019 The study involved proposing a tuned mass damper (TMD) system with a novel mechanism for supporting the mass, which is called the two‐phase support (TPS) mechanism.
Takayuki Sone +7 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Optimizing accessibility in the home office: implications of accessible kitchen design literature
, 2005 Kitchen design is an important phase of the overall field of residential design. On the basis of cost alone, the residential kitchen assumes a role of major import because it is the room with the highest cost per square foot. Moreover, when designing the
Her, YeaWon
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Mobility Oriented Design: The Case for Miami’s Metrorail
, 2022 Mostafavi, M., Waldheim, C. & Keenan, J.M. (2018). Mobility Oriented Design: The Case for Miami’s Metrorail. Cambridge, MA.: Office for Urbanization, Harvard Graduate School of Design.Mobility Oriented Design (MOD): The Case of Miami Metrorail ...
Mostafavi, Mohsen +2 more
core
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
ArchitectureIndoor environmental quality (IEQ) is increasingly recognized as a critical factor in shaping employee well-being, satisfaction, and work performance, particularly in hybrid workplace settings.
Nasrin Golshany +3 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Alternative office design, Romanesque
, 2023 Item 3633 - 1 Album: New offices, CSR office building under construction, Bent Street, Sydney, exterior views, interior views, laboratories, drawing office and board ...
Architect: Harold O. Jackson +1 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source