Results 91 to 100 of about 3,426,445 (329)

Comparative studies of offices pre and post — how changing spatial configurations affect organisational behaviours [PDF]

open access: yes, 2009
Understanding the way in which design interventions in an office affect everyday users, and thus shape organisational behaviour, should be high on the agenda for architects, designers and consultants alike. Surprisingly, this seems rarely to be the case.
Budgen, A.   +4 more
core  

Trans-dimensional inversion of modal dispersion data on the New England Mud Patch [PDF]

open access: yes, 2019
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Bonnel, J., Dosso, S. E., Eleftherakis, D., & Chapman, N. R.
Bonnel, Julien   +3 more
core   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Does public transit use increase the economic efficiency of urban areas?

open access: yesJournal of Transport and Land Use, 2012
This paper explores the relationship between the scale of public transit services in urban areas of the U.S. and the efficiency of those economies, with efficiency measured by commercial office rents.
Mathew Drennan, Charles Brecher
doaj   +1 more source

Holding periods and investment performance: analysing UK office returns 1983-2003 [PDF]

open access: yes, 2005
Drawing on a unique database of office properties constructed for Gerald Eve by IPD, this paper examines the holding periods of individual office properties sold between 1983 and 2003. It quantifies the holding periods of sold properties and examines the
Gardner, A., Matysiak, George
core  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Baring some essentials: boys' achievement, ERO and leadership. [PDF]

open access: yes, 2000
This article identifies some popular concerns about boys' achievement, and concerns raised by researchers. The Education Review Office report on the achievement of boys is critiqued in relation to the role masculinities play in regulating boys' attitudes
Wright, Noeline
core   +1 more source

A highly scalable Met Office NERC Cloud model [PDF]

open access: yes, 2015
Large Eddy Simulation is a critical modelling tool for scien- tists investigating atmospheric flows, turbulence and cloud microphysics. Within the UK, the principal LES model used by the atmospheric research community is the Met Office Large Eddy Model ...
Allen, Thomas   +6 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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