Results 171 to 180 of about 937,523 (287)

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, Volume 13, Issue 9, 13 February 2026.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Advanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +1 more source

The volume of outpatient office visits did not increase for specialties that were more likely to adopt telehealth. [PDF]

Health Aff Sch
Lee JD, Chun E, Chang CH, Hou H, Liu T, Dunn RL, McCullough JS, Thompson MP, Ellimoottil C.   +8 more
europepmc   +1 more source

Redundancy of Progress Notes for Serial Office Visits. [PDF]

Ophthalmology, 2020
Hribar MR, Rule A, Huang AE, Dusek H, Goldstein IH, Henriksen B, Lin WC, Igelman A, Chiang MF.   +8 more
europepmc   +1 more source

Increased Blood Flow and Tendon Swelling Precedes Vascular Expansion and Tissue Matrix Changes In Early Human Tendinopathy: A Potential Window for Superior Treatment Response

Advanced Science, EarlyView.
Human participants with early‐ or chronic‐stage tendinopathy and healthy controls are investigated using ultrasound Doppler, 3T and 7T MRI, and tendon biopsies. Tendon swelling and hyperperfusion are evident early, while vascular growth and extracellular matrix changes are most pronounced in chronic tendinopathy. Early intervention may provide superior
Max F. R. Merkel, Nikolaj M. Malmgaard‐Clausen, Marius Lendal, Hartwig R. Siebner, René B. Svensson, Stephanie G. Dakin, Marcus Krüger, Luisa Schmidt, Jakob Agergaard, Ching‐Yan Chloé Yeung, S. Peter Magnusson, Michael Kjaer   +11 more
wiley   +1 more source

Economic impact of reduced postoperative visits after inflatable penile prosthesis implantation

Journal of Comparative Effectiveness Research
Aim: This study assessed the economic impact of reducing one postoperative visit following inflatable penile prosthesis (IPP) implantation. Methods: Scenario analyses were used to model the effects of eliminating one 30-min IPP postoperative visit from
Bradley Gill, Young Eun Shin, Kathryn Durand, Andrew Sun, Paurush Babbar, Sirikan Rojanasarot   +5 more
doaj   +1 more source

Patient-Oncologist Communication Regarding Oral Chemotherapy During Routine Office Visits. [PDF]

JCO Oncol Pract, 2020
Nguyen BKH, Wu BS, Sanoff HK, Lafata JE.
europepmc   +1 more source

Convergent and Divergent Connectivity Patterns of the Arcuate Fasciculus in Macaques and Humans

Advanced Science, EarlyView.
This study employs viral‐based single‐neuron tracing and dMRI‐based whole‐brain tractography to investigate arcuate fasciculus (AF) trajectories in macaque monkeys, and compares with the human AF connectome using spectral embedding. Results demonstrate conserved AF topography spanning temporoparietal‐auditory‐frontal pathways across primates, with ...
Jiahao Huang, Ruifeng Li, Wenwen Yu, Anan Li, Xiangning Li, Mingchao Yan, Lei Xie, Qingrun Zeng, Xueyan Jia, Shuxin Wang, Ronghui Ju, Feng Chen, Qingming Luo, Hui Gong, Andrew Zalesky, Xiaoquan Yang, Yuanjing Feng, Zheng Wang   +17 more
wiley   +1 more source

Hybrid care model: Combining telemedicine and office visits for diabetes management in older adults with type 1 diabetes. [PDF]

Med Res Arch
Toschi E, Adam A, Frimpong N, Hurlbert R, Slyne C, Laffel L, Munshi M.   +6 more
europepmc   +1 more source

A Novel 10‐Protein Score for Liver Fat Content Predicts Cardiovascular‐Kidney‐Metabolic Disease Risk

Advanced Science, EarlyView.
A novel 10‐protein plasma score precisely quantifies liver fat, outperforming the fatty liver index. It robustly predicts the risk of numerous cardiovascular‐kidney‐metabolic diseases and integrates with genetic data for precision prevention, offering a practical alternative to magnetic resonance imaging (MRI). Abstract Liver fat content (LFC) is a key
Xiaoqin Gan, Yuanxiu Wei, Yiting Wu, Xinyue Su, Gangling Wang, Sisi Yang, Ziliang Ye, Yanjun Zhang, Hao Xiang, Yu Huang, Yiwei Zhang, Yuanyuan Zhang, Xianhui Qin   +12 more
wiley   +1 more source