Results 201 to 210 of about 934,771 (266)

The True Cost of Heat: Evaluating Heat-Related Mortality Estimation Methods in Texas. [PDF]

Geohealth
Rutt JRJ, Dessler AE.
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Published Salmonella risk assessment model contains major errors and inconsistencies - ERRATUM. [PDF]

Epidemiol Infect
Powell M, Ebel E.
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Assessing the efficacy of a community-based COVID-19 program with vulnerable and underserved Latino communities. [PDF]

Discov Public Health
Marsiglia FF, Lee SK, Oh H, Ayers Vollrath S, De La Rosa K, Zindani A, Kulis S.   +6 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

A 2000-2023 dataset for measuring China's biodiversity risk. [PDF]

Data Brief
Chen ZH, Gao X, Yang JR, Yarovaya L.
europepmc   +1 more source

Improving Bovine Tuberculosis Surveillance Through Risk-Based Prioritization of Slaughterhouse-Triggered Trace-Back Investigations. [PDF]

Animals (Basel)
Lourenço LFC, Mendes RE.
europepmc   +1 more source

Language-related self-efficacy of pharmacy staff in providing medication counselling to older adults in a linguistically diverse setting. [PDF]

Explor Res Clin Soc Pharm
Suppiah SD, Goh M, Yang X, Tan YW, Malhotra R, PROMISE Study Group.   +5 more
europepmc   +1 more source