Results 31 to 40 of about 934,771 (266)

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

Officiers « moyens », officiers seigneuriaux [PDF]

Les Cahiers du Centre de recherches historiques, 2001
La croissance de l'Etat d'offices dont les effectifs enflent du regne de Francois Ier a celui de Louis XIV de 4 000 a environ 46 000, est une realite bien etablie. Au xviiie siecle, le mouvement persiste et, meme si son ampleur est moindre, il y a dans les annees 1750-1760, pres de 65 000 officiers royaux de finance et de justice dans le pays.
openaire   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source

Integration of newborn screening for sickle cell disease into primary health care in Bukavu, Democratic Republic of the Congo: a pilot study

BMC Primary Care
Introduction Sickle cell disease (SCD) is an inherited genetic disorder that represents a major public health challenge in sub-Saharan Africa, particularly in the Democratic Republic of the Congo (DRC).
Nash Mwanza Nangunia, Olivier Mukuku, Viviane Bianga Feza, Yves Mulindilwa Kyembwa, Théophile Barhwamire Kabesha, Zacharie Kibendelwa Tsongo, André Kabamba Mutombo, Stanislas Okitotsho Wembonyama   +7 more
doaj   +1 more source

Variables influencing the distribution of freshwater mollusk intermediate hosts of Schistosoma mansoni in the Oicha Health Zone, North Kivu Province, Democratic Republic of the Congo

Orapuh Journal
Introduction Schistosomiasis caused by Schistosoma mansoni remains a major neglected tropical disease in sub-Saharan Africa, where transmission depends on freshwater snail intermediate hosts.
PASCAL BAILANDA MUMBERE, Théophile Barhwamire Kabesha, Walere Muhindo sahani, Louis Paluku Sabuni, Oscar Wembo Ndeo   +4 more
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

Assessment of healthcare workers’ knowledge and availability of resources for sickle cell disease management in Bukavu, Democratic Republic of the Congo

BMC Health Services Research
Introduction Sickle cell disease (SCD) is a global public health priority due to its high morbidity and mortality. In the Democratic Republic of the Congo (DRC), effective care for this disease depends on the availability of resources and the level of ...
Nash Mwanza Nangunia, Olivier Mukuku, Viviane Bianga Feza, Yves Mulindilwa Kyembwa, Théophile Barhwamire Kabesha, André Kabamba Mutombo, Stanislas Okitostho Wembonyama   +6 more
doaj   +1 more source

DEBATE ABOUT GUBERNSKIE VEDOMOSTY IN CAPITAL CITY AND LOCAL PRESS IN THE BEGINNING OF XX CENTURY

Гуманитарные и юридические исследования, 2021
The article deals with archival materials about discussion in pre-revolutionary press of the typological specifics, place and the role of government gubernskie vedomosty in the printing system in the beginning of XX century.
Y. A. Klets
doaj