Results 221 to 230 of about 15,992,886 (292)

Grassroots Governance for Sustainable Environmental Planning: Examining Manila Bay as Limit Case for Participatory Policy Implementation. [PDF]

Environ Manage
Gonzalez Benson O, Juárez N.
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Partnerships That Leverage Existing Community Strengths Are Key to Improving Cardiovascular Health. [PDF]

Circulation
Powell-Wiley TM.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Field evaluation of SumiLarv^™ 2MR larvicide for controlling the invasive malaria vector Anopheles stephensi in Ethiopia: a randomised controlled trial. [PDF]

Malar J
Dagne A, Doumbe-Belisse P, Degefa T, Zeynudin A, Lukas B, Eyasu A, Eba K, Jaiteh F, Geleta D, Lejore E, Erena E, Simma EA, Grietens KP, Weetman D, Donnelly MJ, Reynolds AM, Wilson AL, Yewhalaw D.   +17 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Better Health for All in a Changing World: Sparks From the 14th ECTMIH. [PDF]

Trop Med Int Health
Albonico M, Awa N, Eggers Y, Köhler C, May J, Rabl D, Schneitler S, Jara-Reznakova B, Rausche P.   +8 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Building the foundation: Training, stakeholder engagement, and planning for Common Elements Treatment Approach (CETA) implementation in Uganda. [PDF]

PLOS Glob Public Health
Miller AP, Rivera Saldaña CD, Kiene SM, Menya E, Figge C, Lukwata Sentongo H, Byansi W, Mugamba S, Kalani Okware K, Tuhebwe D, Murray L, Mwanza D, Nalugoda F, Watya S, Ddaaki W, Daama A, Bulamba R, Nkale J, Kyasanku E, Kigozi G, Kigozi Nalwoga G, Nakigozi G.   +21 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source