Results 271 to 280 of about 1,331,013 (334)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Should I Have to Pay to Work? On Responsibility for the Cost of Disability Accommodations. [PDF]

Disabil Soc
Mintz KT.
europepmc   +1 more source

Does the regulatory quality matter in the relationship between climate finance and inclusive growth in Africa? [PDF]

PLoS One
Ayana ID.
europepmc   +1 more source

Rethinking drug resistance in focal cortical dysplasia-related epilepsy. [PDF]

Epilepsia
Cohen NT, Oluigbo CO, Perry MS, Gaillard WD.   +3 more
europepmc   +1 more source

Determinants of access to waste management services in healthcare facilities in 14 low- and middle-income countries. [PDF]

Waste Manag Res
Tantum LK, Anderson DM, Pieper U, Cronk R.   +3 more
europepmc   +1 more source

Why Medical Education Without Artificial Intelligence Still Matters: A Neuroscience-Informed Perspective.

JMIR Med Educ
Verdonk C.
europepmc   +1 more source

Microbiology of the Built Environment: Applying Our Knowledge for Healthy Indoor Spaces. [PDF]

Environ Sci Technol
Dannemiller KC, Nastasi N, Ganguly A, Bibby K, Hegarty B.   +4 more
europepmc   +1 more source

Limiting the health impact of earthquakes: a call to action. [PDF]

J Glob Health
Popescu C, Kayano R, Nabeth P.
europepmc   +1 more source

Does Official Development Assistance Promote Foreign Direct Investment? [PDF]

Koyama, Naonori and Eau-tin Jen
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