Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
The Geographical Allocation Pattern of Spanish Official Development Assistance [PDF]
The geographical allocation of Spanish aid has been little studied, despite the fact that it is unusually concentrated on middle-income countries. This paper sets out a model of Spanish ODA policy based on an integrated approach reflecting recipient ...
Sergio Tezanos Vazquez (ICEI and QEH)
core
Official Development Assistance (ODA) is a technical term defined by the OECD. One of the main categories of Japan ODA is bilateral grants which facilitate transfer of technology, skills and knowledge.
Kamigwi Antony G
core +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Economic Determinants of Foreign Direct Investment in Armenia, Kyrgyz Republic and Turkmenistan: Theory and Evidence [PDF]
The aim of the present study is to investigate the effects of different economic determinants on foreign direct investment (FDI) for three countries selected from Central Asia namely Armenia, Kyrgyz Republic and Turkmenistan.
Muhammad AZAM
doaj
Development Assistance and Development Finance: Evidence and Global Policy Agendas [PDF]
official development assistance, growth, poverty, Millennium Development Goals, sub-Saharan Africa, Pacific, innovative ...
Addison, Tony +2 more
core
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Dentro o más allá de la ayuda: el difícil camino de la Coherencia de Políticas para el Desarrollo
Analyses of Policy Coherence for Development (PCD) began to arise in the OECD more than two decades ago. These approaches have evolved while the discussions about the necessary reform of the system of international cooperation were taking place. However,
Gutiérrez-Goiria, J. +2 more
doaj
Main characteristics of Japanese Official Development Assistance (ODA) flows [PDF]
At the end of the 1990s, the Japanese government distributed annually more than US$10 billion as foreign aid directly or indirectly to developing countries.
Furuoka, Fumitaka
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

