BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
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Drug-Induced Liver Injury with Novel Fat Burner AlbutarexV2 in an Active Duty Sailor. [PDF]
Lilley LJ, Wiseman M, Sadowski B.
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Richard McDonald, Plaintiff, v. Pennsylvania State Police; Colonel Frank Pawlowski, Commissioner of Pennsylvania State Police in his official capacity; Major John Gallaher, in his individual capacity, Defendants. [PDF]
McVerry, Judge Terrence J.
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Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
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<i>Candida auris</i> surveillance in the Military Health System: a multidrug-resistant threat. [PDF]
Brough JJ +12 more
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Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
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The threat to person-centered care: how censoring healthcare language endangers public health. [PDF]
Barello S, Romão ME.
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Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
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Outcome and predictors of response to vagus nerve stimulation for drug-resistant epilepsy: a retrospective cohort study. [PDF]
Crutcher R, Horvat D, Lehman N, Ma Y.
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Rose, Town of and Highway Unit, International Brotherhood of Teamsters (IBT), Local 118 (2007) [PDF]
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