Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Views on fall prevention among multi-disciplinary healthcare workers. [PDF]
BioinformationD G, P V, M AP.
europepmc +1 more source
Schaghticoke, Town of and Highway Unit, International Brotherhood of Teamsters (IBT), Local 294 (2008) [PDF]
, 2008 core +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
The principle of stewardship truthful communication for the restoration of trust in public health officials. [PDF]
J Public Health (Oxf)de Campos-Rudinsky TC.
europepmc +1 more source
Binghamton, City of and Binghamton Police Benevolent Association (2002) [PDF]
, 2002 core +1 more source
The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen +5 more
wiley +1 more source
Management of glenohumeral osteoarthritis in the younger patient: A population level analysis of usual care delivery in a large health system. [PDF]
Osteoarthr Cartil OpenRhon DI, Horn ME, Milan R, George SZ.
europepmc +1 more source
Montgomery County Board of Education and Montgomery County Council of Supporting Services Employees (1982) [PDF]
, 1982 core +1 more source
Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin +2 more
wiley +1 more source