Results 91 to 100 of about 191,060 (306)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Spoken language corpora for the nine official African languages of South Africa

open access: yes, 2003
In this paper we give an outline of a corpus planning project which aims to develop linguistic resources for the nine official African languages of South Africa in the form of corpora, more specifically spoken language corpora.
Hendrikse, A. P., Allwood, Jens,
core  

The Use of Official Languages Act: Diversity Affirmed?

open access: yesPotchefstroom Electronic Law Journal, 2017
A full sixteen years after the coming into force of the 1996 Constitution, Parliament responded to the constitutional obligation to regulate and monitor, by legislative and other means, the use of official languages by adopting the Use of Official Languages Act 12 of 2012.
openaire   +6 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

The Hausa factor in the choice of an official (national) language in Nigeria: Cleavages and conflicts in Nigerian political debates

open access: yesStudies in African Languages and Cultures, 1996
This paper proposes to discuss how ethnic and sub-ethnic sensitivities in Nigeria have been sharpened over language matters by examining some landmarks in the Nigerian discourse on an official (national) language and to survey the concomitant tensions ...
Andrew Haruna
doaj  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

English language policy and planning in Iran

open access: yes, 2011
Iran has been in the headlines in the recent years and decades for many socio-political reasons. Many of these involve the confrontation between Islamic revolutionary values and the foreign policies and aspirations of Western governments.
Jamshidifard, Saman
core  

Language law and language rights: perspectives on legal intervention and language diversity

open access: yesActa Academica, 2009
Language legislation aims to protect or promote the status and use of one or more specified languages. Official language legislation relates to the according of official status to a language or languages, while liberal language legislation pertains to ...
Joseph-G Turi
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy