Results 261 to 270 of about 1,455,130 (355)

A Dataset Showing a Century of Evolution in the Complexity of the United States Legal Code. [PDF]

Sci Data
Jeong D, Holehouse J, Yoon J, Kempes CP, West GB, Youn H.   +5 more
europepmc   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Burden of Mental and Behavioral Disorders in Colombia, 2022: A Subnational Analysis Based on Disability-Adjusted Life Years. [PDF]

Int J Environ Res Public Health
Quintero Díaz KJ, Gutierrez Lesmes OA, Salamanca Ramos E.   +2 more
europepmc   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Assessing the composition of nurses in South Africa versus the WHO perspective. [PDF]

Curationis
Abrahams F, Brijball Parumasur S.
europepmc   +1 more source

IMPROVING THE COLLECTION AND QUALITY OF OFFICIAL STATISTICS DATA AS A FACTOR OF INCREASING THE VALUES AND ACCURACY OF KEY MACROECONOMIC INDICATORS FOR FORECASTING BY THE EXAMPLE OF THE "INVESTMENT IN FIXED CAPITAL" INDICATOR IN MOSCOW

Aleksey Vedev, Aleksandra Silchuk, Vladimir Eremkin, Konstantin Tuzov, M. A. Kovaleva   +4 more
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Rethinking the way we measure access to language-concordant health services for minority language populations: a secondary analysis of publicly available physician and population data in Ontario, Canada. [PDF]

BMJ Open
Timony PE, Belanger C, Bélizaire A, Desilets A, Gauthier A, Karunananthan S, Muray MN, Peixoto C, Fitzsimon JP, Godfrey L, Bjerre LM.   +10 more
europepmc   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Maternal mortality in the Republic of Cyprus: Insights from population-based observations 2004-2022. [PDF]

Eur J Midwifery
Hadjigeorgiou E, Piri V, Sarantaki A, Tigka M, Diamanti A, Karampas G, Metallinou D.   +6 more
europepmc   +1 more source