Results 51 to 60 of about 308,216 (249)
Corrigendum: Efficient and reliable geocoding of German Twitter data to enable spatial data linkage to official statistics and other data sources. [PDF]
Front Sociol, 2022 Nguyen HL +4 more
europepmc +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
National Vital Statistics System improvements [PDF]
The National Vital Statistics System (NVSS) provides the nation\u2019s official vital statistics based on the collection and registration of birth and death events at the state and local level. This system contains information on all births and deaths in
core +6 more sources
Efficient and Reliable Geocoding of German Twitter Data to Enable Spatial Data Linkage to Official Statistics and Other Data Sources. [PDF]
Front Sociol, 2022 Nguyen HL +4 more
europepmc +1 more source
Molecular Oncology, Volume 20, Issue 6, Page 1513-1534, June 2026.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Urban and Rural Population and Development Research on Medical Coordination: In View of Dalian 2008-2017 Official Statistics. [PDF]
Int J Environ Res Public Health, 2021 Qiu Y, Lu W, Guo J, Sun C, Jia P.
europepmc +1 more source
Molecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, Volume 20, Issue 6, Page 1612-1625, June 2026.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Foundations and Advances of Machine Learning in Official Statistics
This Open access book gives an overview of current research and developments on the incorporation of machine learning in official statistics. It covers methodological questions, practical aspects and cross-cutting issues.
core +1 more source