Results 81 to 90 of about 1,455,130 (355)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Recording of Alcohol in Official Crash Statistics: Underreporting and Procedures to Improve Statistics

Journal of Road Safety, 2018
Worldwide 1.25 million people die in road crashes every year and it is widely recognized that drink driving is an important risk-increasing factor. Official statistics of alcohol-related crashes are likely to underestimate alcohol-related crashes and ...
Luuk Vissers, Sjoerd Houwing, Fred Wegman   +2 more
doaj  

Corrigendum: Efficient and reliable geocoding of German Twitter data to enable spatial data linkage to official statistics and other data sources. [PDF]

Front Sociol, 2022
Nguyen HL, Tsolak D, Karmann A, Knauff S, Kühne S.   +4 more
europepmc   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Metadata Management in Official Statistics–An IT-based Methodology Approach

Austrian Journal of Statistics, 2016
There is a considerable impact of evolving information technology (IT) on Official Statistics. Coping with both risks and potentials of this development, Official Statistics is in serious need to address questions of keeping the statistical system ...
Karl A. Froeschl
doaj   +1 more source

Efficient and Reliable Geocoding of German Twitter Data to Enable Spatial Data Linkage to Official Statistics and Other Data Sources. [PDF]

Front Sociol, 2022
Nguyen HL, Tsolak D, Karmann A, Knauff S, Kühne S.   +4 more
europepmc   +1 more source

Factor Structural Time Series Models for Official Statistics with an Application to Hours Worked in Germany [PDF]

, 2018
Roland Weigand, Susanne Wanger, Ines Zapf   +2 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The Future of Federal Statistics: World Statistics Day Webinar—20 OCTOBER 2020

Harvard Data Science Review, 2021
John Pullinger
doaj   +1 more source

IMPLEMENTATION OF BIG DATA IN OFFICIAL STATISTICS

Journal of Business Paradigms, 2018
Big data is a huge resource that needs to be used at all levels of economic planning. The article is devoted to the study of the development of the concept of “Big Data” in the world and its impact on the transformation of statistical simulation of ...
Aliaksei Zhurauliou, Oleksii Simachov
doaj