Results 81 to 90 of about 308,216 (249)

RR by R in Official Statistics

open access: yes, 2016
Nowadays there is a growing alarm about scientific research results that cannot be reproduced. The reasons comprise increased levels of control, complexity of experiments and statistics, and also time pressures on researchers.
Nicoleta CARAGEA, Ciprian ALEXANDRU
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Editorial. Special Issue on Official Statistics

open access: yes, 2014
This is my first volume as the new editor of the Austrian Journal of Statistics. Naturally, some changes have been realized concerning the style and public appearance of the journal.
Templ, Matthias
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Sociology : using official statistics

open access: yes, 2005
Guide to using official statistics. Study materials looking at research methods used in sociology, types of data, use of official statistics and validity of statistics. Includes interactive self assessment exercises and a glossary.
Pete Richardson, Coleg Llandrillo Cymru
core  

The use of administrative data in official statistics - past, present and future : with special reference to the Nordic countries [PDF]

open access: yes, 2010
Published 2010 by the Department of Statistics, Stockholm University: Stockholm, Sweden (in collaboration with Statistics Sweden). Kapittelet er gjengitt med tillatelse fra Stockholm Universitet, Statistiska institutionen.The rolls, from which conscripts
Nordbotten, Svein
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Official Statistics [PDF]

open access: yesAmerican Journal of Sociology, 1898
openaire   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy