Results 41 to 50 of about 1,014,492 (237)

A Situational Assessment of the Diagnostic Landscape and Organizational Readiness to Implement Next‐Generation Sequencing at Two Childhood Cancer Treatment Centers in Ghana

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Next‐generation sequencing (NGS) has emerged as a promising approach to improve diagnostic accuracy, but its feasibility in low‐ and middle‐income countries remains unknown. This study characterized the diagnostic landscape and assessed organizational readiness for NGS implementation at two childhood cancer treatment centers in Accra ...
Melissa Carvalho   +6 more
wiley   +1 more source

Seasonal and Interannual Variability of Columbia Glacier, Alaska (2011–2016): Ice Velocity, Mass Flux, Surface Elevation and Front Position

open access: yesRemote Sensing, 2017
Alaskan glaciers are among the largest contributors to sea-level rise outside the polar ice sheets. The contributions include dynamic discharge from marine-terminating glaciers which depends on the seasonally variable ice velocity.
Saurabh Vijay, Matthias Braun
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola   +4 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

High-Precision Tracking of Free-Space Optical Communication System on Mobile Platforms

open access: yesPhotonics
We propose a new free-space optical (FSO) communication system for moving platform tracking, which can achieve high precision aiming and tracking. Our prototype system consists of three parts.
Ning Sun   +3 more
doaj   +1 more source

Angular offset distributions during fixation are, more often than not, multimodal

open access: yesJournal of Eye Movement Research, 2021
Typically, the position error of an eye-tracking device is measured as the distance of the eye-position from the target position in two-dimensional space (angular offset).  Accuracy is the mean angular offset.
Lee Friedman   +3 more
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Self-correcting Bayesian target tracking [PDF]

open access: yes, 2015
The copyright of this thesis rests with the author and no quotation from it or information derived from it may be published without the prior written consent of the authorAbstract Visual tracking, a building block for many applications, has challenges ...
Biresaw, Tewodros Atanaw
core   +4 more sources

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