Structural Insights into the HWE Histidine Kinase Family: The Brucella Blue Light-Activated Histidine Kinase Domain [PDF]
, 2016 In response to light, as part of a two-component system, the Brucella blue light-activated histidine kinase (LOV-HK) increases its autophosphorylation, modulating the virulence of this microorganism.
Arrar, Mehrnoosh +9 more
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Neuroprotection targeting protein misfolding on chronic cerebral hypoperfusion in the context of metabolic syndrome [PDF]
, 2018 Metabolic syndrome (MetS) is a cluster of risk factors that lead to microvascular dysfunction and chronic cerebral hypoperfusion (CCH). Long-standing reduction in oxygen and energy supply leads to brain hypoxia and protein misfolding, thereby linking CCH
Capani, Francisco +6 more
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Prolactin and its receptor as therapeutic targets in glioblastoma multiforme [PDF]
, 2019 Although prolactin (PRL) and its receptor (PRLR) have been detected in glioblastoma multiforme (GBM), their role in its pathogenesis remains unclear. Our aim was to explore their contribution in GBM pathogenesis.
Abt, Araceli +13 more
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Platelet Apoptosis in Adult Immune Thrombocytopenia: Insights into the Mechanism of Damage Triggered by Auto-antibodies [PDF]
, 2016 Mechanisms leading to decreased platelet count in immune thrombocytopenia (ITP) are heterogeneous. This study describes increased platelet apoptosis involving loss of mitochondrial membrane potential (ΔΨm), caspase 3 activation (aCasp3) and ...
Contrufo, Geraldine +11 more
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Kiri-Kerê - Pesquisa em Ensino, 2022 Este artigo parte de uma experiência situada em uma pesquisa, na qual, entre outras ações, foram propostas oficinas com a participação de crianças matriculadas em uma instituição de Educação Infantil, em Vitória/ES, e seus familiares. Este texto analisa, então, um dos encontros da oficina, o qual teve como disparador um texto literário em torno do qual
Flávia Amorim Sperandio +2 more
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Cardiorenal Involvement in Metabolic Syndrome Induced by Cola Drinking in Rats: Proinflammatory Cytokines and Impaired Antioxidative Protection [PDF]
, 2016 We report experimental evidence confirming renal histopathology, proinflammatory mediators, and oxidative metabolism induced by cola drinking. Male Wistar rats drank ad libitum regular cola (C, = 12) or tap water (W, = 12). Measures.
Ambrosio, Giuseppe +7 more
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Territorios, 2022 El proceso descrito en este texto tiene como objetivo mejorar el análisis y planificación de la movilidad urbana, tal que, expongan el nivel de inclusión y equidad de una porción de ciudad, identificando falencias en el acceso a equipamientos urbanos ...
Carlos Ernesto Grande Ayala +4 more
doaj +1 more source
Acid-sensing ion channels 1a (ASIC1a) inhibit neuromuscular transmission in female mice [PDF]
, 2014 Acid-sensing ion channels (ASIC) open in response to extracellular acidosis. ASIC1a, a particular subtype of these channels, has been described to have a postsynaptic distribution in the brain, being involved not only in ischemia and epilepsy, but also ...
Colettis, Natalia Claudia +8 more
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On complementable operators in the sense of T. Ando [PDF]
, 2020 Consider an operator A :H→K between Hilbert spaces and closed subspaces S ⊂ H and T ⊂ K. If there exist projections E on H and F on K such that R(E) =S, R(F) =T and AE=F∗A then A is called (S, T)-complementable.
Arias, Maria Laura +2 more
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TRPV4 Contributes to Resting Membrane Potential in Retinal Müller Cells: Implications in Cell Volume Regulation [PDF]
, 2017 Neural activity alters osmotic gradients favoring cell swelling in retinal Müller cells. This swelling is followed by a regulatory volume decrease (RVD), partially mediated by an efflux of KCl and water. The transient receptor potential channel 4 (TRPV4),
Capurro, Claudia Graciela +7 more
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