Results 11 to 20 of about 16,974 (127)

Safety of sulfamethoxazole-trimethoprim for the treatment of bacterial infection in outpatient settings: A systematic review and meta-analysis with active comparator disproportionality analysis. [PDF]

Br J Clin Pharmacol
Aims Sulfamethoxazole–trimethoprim (SMX‐TMP) is a widely used antibiotic for treating bacterial infections, but its safety in adult outpatients remains understudied. This systematic review and meta‐analysis evaluated the safety profile of SMX‐TMP and identified critical research gaps.
Preyra R, Eddin LE, Ahmadi F, Jafari A, Muanda FT.   +4 more
europepmc   +3 more sources

Europe's contribution to the evaluation of the use of systemic antimicrobials in the treatment of periodontitis

Periodontology 2000, EarlyView., 2023
Abstract This narrative review celebrates Europe's contribution to the current knowledge on systemically administered antimicrobials in periodontal treatment. Periodontitis is the most frequent chronic noncommunicable human disease. It is caused by dysbiotic bacterial biofilms and is commonly treated with subgingival instrumentation.
David Herrera, Arie Jan van Winkelhoff, Paula Matesanz, Katalina Lauwens, Wim Teughels   +4 more
wiley   +1 more source

Supra and subgingival application of antiseptics or antibiotics during periodontal therapy

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero, Jorge Serrano, Nicole Birgit Arweiler, Thorsten Mathias Auschill, Ali Gürkan, Gülnur Emingil   +5 more
wiley   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Manipulating Charge Dynamics in Carbon Nitride by Carbon Dot Doping for Efficient Photocatalysis

Advanced Science, EarlyView.
A series of carbon dot (CD) doped graphitic carbon nitride (g‐C3N4) materials have been rationally synthesized, which exhibited different photophysical properties, excitonic behaviors, and photocatalytic degradation activities. It provides valuable insights to deepen the understanding of exciton dynamics based on g‐C3N4 materials, and rational design ...
Lingfeng Ouyang, Maggie Ng, Zhang‐Hong Zhou, Hao Wu, Man‐Chung Tang, Season Si Chen   +5 more
wiley   +1 more source

Amorphous Engineering Driving d‐Orbital High Spin Configuration for Almost 100% 1O2‐Mediated Fenton‐Like Reactions

Advanced Science, EarlyView.
Through an amorphization strategy, the electronic structure of single‐atom Co is effectively modulated from a low spin state (Co‐CCN) to a high spin state (Co‐ACN). The rearrangement of the electronic configuration optimizes the d‐band center resulting in the selectivity of 1O2 with almost 100%.
Juanjuan Qi, Qian Bai, Xiuhui Bai, Hongfei Gu, Siyue Lu, Siyang Chen, Qiangwei Li, Xudong Yang, Jianhui Wang, Lidong Wang   +9 more
wiley   +1 more source

Emergence of Staphylococcus aureus Resistance to Antimicrobial Peptides Nisin, NZ2114 and Bacitracin Involves Multiple Phenotypic Changes

Animal Research and One Health, EarlyView.
The AMP‐induced mutant Staphylococcus aureus strain nzR showed increased resistance, five gene mutations, and decreased surface anion levels. AMPs affect the NDH‐2 protein encoded by ndh gene inhibiting the growth of S. aureus. The deletion of the ndh gene promotes the development of AMPs resistance.
Lingyu Xiao, Xingyuan Ma, Ping Tian, Lianbin Li, Zafir Muhammad, Xiaokun Wang, Xuemei Xue, Jinhe Xiao, Liangjun Zheng, F. A. El‐Gohary, Xin Zhao, Junning Pu, Huping Xue   +12 more
wiley   +1 more source

Corn cob pyrolysis: A systematic literature review of methods and applications

The Canadian Journal of Chemical Engineering, EarlyView.
Mapping the research landscape of corn cob pyrolysis. Abstractas The agricultural sector is experiencing a surge in waste generation due to population growth, creating an urgent need to convert byproducts into value‐added products. Maize (Zea mays L.), a leading global crop, produces significant byproducts, such as corn cob, which are often undervalued.
Vilmar Steffen, Maiquiel Schmidt de Oliveira, Lais da Silva Pego Hericks, Schaline Winck Alberti, Marlon Henrique da Silva, Edson Antonio da Silva   +5 more
wiley   +1 more source

Applications of bioactive herbal extracts in dressing materials for skin wound repair: Ingredients, mechanisms and innovations

Interdisciplinary Medicine, EarlyView.
Abstract The skin, as the body's largest organ, plays essential roles in protection, immune regulation, and homeostasis. Skin trauma, especially chronic wounds such as diabetic ulcers, poses significant clinical challenges. Traditional treatments, while often effective, can be costly and pose risks.
Boxiang Yang, Jingyuan Xu, Siyi Liu, Chaoying Wu, Yi Li, Mingqi Lv, Tingting Chen, Chuanrong Zhao, Daojun Pu, Chaojun Tang, Anna Malashicheva, Guangchao Zang, Guixue Wang   +12 more
wiley   +1 more source

A case of idiosyncratic drug‐induced agranulocytosis because of sulbactam/ampicillin

Journal of General and Family Medicine, EarlyView.
We report a case of agranulocytosis caused by sulbactam/ampicillin. During antimicrobial therapy, close monitoring of total white blood cell counts is essential. Abstract Idiosyncratic drug‐induced agranulocytosis is a rare but life‐threatening condition that requires immediate medical intervention.
Kazuya Toda, Kaku Kuroda, Moe Kuroda, Kota Kawai, Yukihiro Sato   +4 more
wiley   +1 more source