Results 51 to 60 of about 28,700,504 (230)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Equivalent Dielectric Permittivity Model of Low Water Cut Oil-Water Two-Phase Flow

Cejing jishu
The capacitance method is widely used to measure the water content of oil-water two-phase flow, whether it is the surface oil-water measurement or the stratification test of the production profile in the well.
QU Jinghui, LIU Xingbin, LIU Dongmei, DENG Yuheng, LIU Dayong, YANG Yuntong   +5 more
doaj   +1 more source

Flow Patterns Transition Law of Oil-Water Two-Phase Flow under a Wide Range of Oil Phase Viscosity Condition

Journal of Applied Mathematics, 2013
A systematic work on the prediction of flow patterns transition of the oil-water two-phase flows is carried out under a wide range of oil phase viscosities, where four main flow regimes are considered including stratified, dispersed, core-annular, and ...
Wei Wang, Wei Cheng, Kai Li, Chen Lou, Jing Gong   +4 more
doaj   +1 more source

Adaptive Kalman Estimation of Phase Holdup of Water-Continuous Oil-Water Two-Phase Flow

IEEE Access, 2017
Phase holdup measurement of the two-phase flow is of significance in industrial process. Accurate and real-time measurement of phase holdup is a critical problem requiring urgent solutions.
Guangzhi Fu, Chao Tan, Hao Wu, Feng Dong
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Study on Oil-Water Two-phase Flow in the Invisible Measuring Pipeline of the Horizontal Tri-electrode Capacitive Sensor

Measurement Science Review
Based on the well logging requirements of horizontal stripper wells, the flow characteristics of the oil-water two-phase flow in the invisible horizontal tri-electrode capacitive sensor (HTCS) measurement pipeline are studied.
Li Lei, Wang Ming, Wang Dahai, Gao Xuewei, Zhu Qianhui   +4 more
doaj   +1 more source

A Unified Model of Oil/Water Two-Phase Flow through the Complex Pipeline

Geofluids, 2021
Oil-water two-phase flow through the complex pipeline, consisting of varying pipes and fittings in series or parallel, is commonly encountered in the petroleum industry.
Qingchun Gao, Zhiming Wang, Quanshu Zeng
doaj   +1 more source

A Review of Progress in Oil-Water Two-Phase Flow Research

Frontiers in Sustainable Development
This paper summarises the current state of research on oil-water two-phase flow, covering flow pattern classification, experimental studies, and model calculations. Common flow patterns and their influencing factors are introduced, and the conversion of different flow types is analyzed.
Yesai Li, Tinglong Hu, Yi Fan, Jiajie Wang   +3 more
openaire   +1 more source

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

FEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source