Nuclear IDH3A Drives Transcriptional Programs in Melanoma via the YBX1–JUN/FOS Axis
Genomic amplification drives aberrant nuclear localization of IDH3A in melanoma. Independent of its canonical metabolic activity, nuclear IDH3A cooperates with YBX1 to activate the c‐JUN/c‐FOS transcriptional program, while NONO facilitates its nuclear localization.
Juan Ran +10 more
wiley +1 more source
Collagen Fibers-Derived Superhydrophobic Foams for High-Performance Separation of Stable Emulsions. [PDF]
Zhan Y +5 more
europepmc +1 more source
High‐Temperature Magnetic Field Mapping Using a Single‐Crystal Diamond MEMS Resonator Array
A single‐crystal diamond MEMS resonator array enables magnetic‐field reconstruction with millisecond response, nanotesla level magnetic noise, and stable operation up to 573 K. Two‐ and three‐dimensional magnetic field mapping are demonstrated using ΔEeffect sensing, highlighting the potential of diamond MEMS technology for hightemperature magnetic ...
Zilong Zhang +4 more
wiley +1 more source
A Comprehensive Systematic Well-to-Refinery Carbon Intensity Assessment of Technoeconomically Viable CO<sub>2</sub>-EOR Operations in Alberta. [PDF]
Jabbar MY +4 more
europepmc +1 more source
PLXDC2 siRNA‐Mediated Intervention Attenuates Microglial Senescence Through cGAS‐STING Signaling
PLXDC2 was identified as a microglial target in Parkinson's disease through human and mouse single‐cell analyses. Ferritin‐armed biomimetic nanovesicles delivered PLXDC2 siRNA, deferoxamine, and CeO2 nanoparticles across the blood–brain barrier, reducing cGAS‐STING activation, iron burden, oxidative stress, and senescence in microglia, thereby ...
Heyue Lu +13 more
wiley +1 more source
A parallel convolution attention network for crop genomic prediction. [PDF]
Peng W, Sheng Y, Zhou Y.
europepmc +1 more source
Alternate‐day fasting suppresses mitochondrial complex II assembly via SDHAF4 to upregulate hepatocyte eNOS. The resulting nitric oxide S‐nitrosylates ATG7 at C184 in hepatic stellate cells, restraining autophagic flux and preventing their profibrotic activation.
Xueqiang Wang +17 more
wiley +1 more source
A catalyst-aware explainable machine learning framework for biodiesel yield prediction over metal-doped biochar and activated carbon catalysts. [PDF]
Ebrahim M +4 more
europepmc +1 more source
After IAV infection, NS1 induces PARP1 phase transition, reducing molecular mobility in condensates, prolonging host transcriptional pause, aiding RdRp cap snatching, and promoting viral transcription. ABSTRACT Influenza A virus (IAV) commandeers host transcriptional machinery to replicate, but mechanisms remain elusive.
Shufeng Ma +12 more
wiley +1 more source
Optimization and Threshold of Soaking Time in Fracturing-Driven Huff-n-Puff for Tight Reservoirs Based on Dynamic Capillary Force. [PDF]
Cheng Q +6 more
europepmc +1 more source

