Results 41 to 50 of about 597,594 (309)
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
How oil majors respond to climate change mitigation in times of crisis significantly impacts the success of the ongoing low-carbon energy transition, especially amid the recent COVID-19 and Russia-Ukraine conflict turbulences.
Wei Ye, Warathida Chaiyapa
doaj +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Building an Early Warning System for Crude Oil Price Using Neural Network
In this paper, a crisis index for the oil price shock is defined and a neural network model is specified for the prediction of the crisis index. This paper contributes to the literature in three ways. First, we build an early warning system for crude oil
Wonho Song
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
We revisit the oil price and stock market nexus by considering the impact of major economic shocks in the post-global financial crisis (GFC) scenario.
Seuk Wai Phoong +2 more
doaj +1 more source
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
EL IMPACTO DE LA CRISIS DEL PETRÓLEO DE 1973 EN EL CONTEXTO ECONÓMICO ESPAÑOL
La crisis del petróleo de 1973 después del corte de suministro de la OPEP a raíz de la guerra de Yom Kippur (octubre de 1973) afecta especialmente a nuestro país tradicionalmente consumidor de altos niveles de energía y una predisposición gubernamental ...
José María Lorca Alcalá
doaj +1 more source
Russian Foreign Policy in Times of Crisis: Greater compliance or resilient self-confidence? CEPS Policy Brief No. 192, 1 July 2009 [PDF]
After months of pretending that the economic turmoil is not likely to affect Russia, the government recently went public on the multiple ramifications of the crisis. It seems that virtually no sector or policy of the Russian state will escape unaffected.
Secrieru, Stanislav.
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