Results 161 to 170 of about 35,482 (264)

RNF13 regulates the endolysosomal pathway through interaction with the small GTPase Arl8B

open access: yesThe FEBS Journal, EarlyView.
The E3 ubiquitin ligase RNF13 functions as a regulatory scaffold, organizing Arl8B‐dependent complexes and tuning downstream signaling that controls endolysosomal organization and trafficking. In this model, wild‐type RNF13 associates with Arl8B on endolysosomes, whereas Arl8B (E22D/F55A) or RNF13 (L244A) variants weaken complex assembly, potentially ...
Audrey M. Sénécal   +4 more
wiley   +1 more source

Nutrient‐specific combinatorial secretion of GLP‐1 and neurotransmitters in the enteroendocrine L‐cell line GLUTag

open access: yesThe FEBS Journal, EarlyView.
Enteroendocrine L cells function as chemosensors in the intestine. Using the L‐cell line GLUTag, we show that distinct nutrients trigger different combinations of co‐secretion of GLP‐1 and neurotransmitters: D‐glucose evokes GLP‐1, glutamate, and ATP; L‐glutamine evokes GLP‐1 and glutamate; sucralose and butyrate evoke only GLP‐1.
Yo Ito   +5 more
wiley   +1 more source

The road to hell is paved with good intentions: A review and research agenda on rebound effects and win–win strategies

open access: yesInternational Journal of Management Reviews, EarlyView.
Abstract Rebound effects describe how efficiency improvements in energy or resource use can increase demand, thereby partially or fully offsetting expected environmental savings. This dynamic complicates win–win strategies that aim to improve environmental and financial performance.
Jozef Cossey, Aurélien Acquier
wiley   +1 more source

Assessing Color Inconstancy of CAD/CAM Materials: Influence of CIE White LED Illuminants and Substrate Shade

open access: yesJournal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective To assess how the CIE white LED illuminants and substrate shade impact the color inconstancy of high‐translucency CAD/CAM materials. Materials and Methods From the spectral reflectance factors of Lava Ultimate‐LU, Grandio blocks‐GB, VITA Enamic‐VE, and VITA Mark II‐M specimens (n = 3/material) measured on nine background shades (ND1 ...
Bruno Arruda Mascaro   +5 more
wiley   +1 more source

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