Results 71 to 80 of about 9,442,008 (320)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Analysis of microscopic pore structure and seepage mechanism of the Fuyang Oil Reservoir in Chaoyanggou Terrace

地质科技通报, 2023
Based on the core samples of the typical channel sandstone from Fuyu and Yangdachengzi Reservoir, CT scanning physical experiments and digital core reconstruction technology were used to characterize the microscopic pore structure and analyze the seepage
Jun Zhao, Wenwen Yan, Tong Xu, Xuejing Bai, Hongmou Zhang, Jisheng Ma, Wei Yang, Yuqing Yang, Qiang Zhao, Dong'an Xue, Zhuo Li, Sihan Li, Lin Cong   +12 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Network traffic anomaly detection model of petroleum industrial control software based on improved grey wolf optimization algorithm

Discover Applied Sciences
To enhance cybersecurity in petroleum industrial control systems, this study proposes a network traffic anomaly detection model based on a Deep Belief Network (DBN) optimized by an Improved Grey Wolf Optimization (IGWO) algorithm.
Bo Yang, Yang Xiao, Xinzhang Wang, Cheng Peng, Xuqing Liu   +4 more
doaj   +1 more source

Doubled haploid ramets via embryogenesis of haploid tissue cultures [PDF]

, 2010
Tissue culture in the oil palm business is generally concerned with the multiplication (clonal production) of dura, pisifera and tenera palms. These are all normal diploids (2n=2x=36).
Caligari, P. D. S., Dunwell, Jim M., Forster, B. P., Iswandar, H. E., Nelson, S. P. C.   +4 more
core  

Novel superhydrophobic and superoleophilic sugarcane green ceramic hollow fibre membrane as hybrid oil sorbent-separator of real oil and water mixture [PDF]

, 2018
The frequent oil spill accidents in nowadays has aroused great attention all over the world. Superhydrophobic and superoleophilic grafted on various substrates have attracted much attention to treat oil and water mixture because of their unique ...
Harun, Zawati, Hubadillah, Siti Khadijah, Jamalludin, Mohd Riduan, Othman, Mohd Hafiz Dzarfan, Yunos, Muhamad Zaini   +4 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Numerical simulation of CO2-ECBM for deep coal reservoir with strong stress sensitivity

Heliyon
CH4 production rate of coalbed methane (CBM) well decreases rapidly during primary recovery in the deeply buried coal seam, resulting in a lot of CH4 residues.
Shengli Gong, Lu Zhang, Tongyao Zhang, Wei He, Weiqiang Hu, Hongchao Yin, Liangshuai Ma, Xin Hong, Wei Zhang, Bo Zhang   +9 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Small scale palm oil producers and supply chains left out from existing certification schemes. [ID781] [PDF]

, 2019
Agricultural history explains most of current palm oil production models (organization of actors including oil palm growers and supply chains). An indigenous non-timber forest product in Central Africa which plant was domesticated and integrated into ...
Durand, Claire, Farago-Szekeres, Tom, Feintrenie, Laurene, Gazull, Laurent, Laumain, Mélanie, Lesage, Colombine, Michel, Isabelle, Pasquis, Richard, Robiglio, Valentina   +8 more
core