Results 141 to 150 of about 81,995 (311)

A Silk Fibroin Nanoparticle Hydrogel Loaded With NK1R Antagonist Has Synergistic Anti‐Inflammatory and Reparative Effects on Dry Eye Disease

open access: yesAdvanced Science, EarlyView.
This study develops a silk fibroin (SF) nanoparticles hydrogel targeting neurokinin 1 receptor with CP‐99994 (CP). Combining CP and SF to form stable nanoparticles while incorporating a flexible hydrogel material results in a sustained‐release ophthalmic drop formulation (SF@CP@Gel), which provides a long‐lasting ophthalmic formulation with anti ...
Bo Gong   +12 more
wiley   +1 more source

BP Rail Logistics Project environmental impact assessment, Bellingham, WA [PDF]

open access: yes, 2013
The purpose of this environmental impact assessment (EIA) is to identify any environmental elements potentially impacted by the BP Cherry Point Refinery Rail Logistics Project, Both on the project site and the land (developed and undeveloped) and water ...
Andrich, Spencer   +4 more
core   +1 more source

Chromatin Organization Governs Transcriptional Response and Plasticity of Cancer Stem Cells

open access: yesAdvanced Science, EarlyView.
Through a combination of transcriptomic and histone mapping studies integrated with chromatin imaging, we define how chromatin organization in nanoscale packing domains fine tunes the plasticity of cancer stem cells (CSCs) driving evasion from and survival after chemotherapy.
Yinu Wang   +20 more
wiley   +1 more source

Plant health index as an anomaly detection tool for oil refinery processes. [PDF]

open access: yesSci Rep, 2022
Al-Anzi FS   +4 more
europepmc   +1 more source

Well-to-Tank Carbon Intensity Variability of Fossil Marine Fuels: A Country-Level Assessment [PDF]

open access: yesarXiv
The transition toward a low-carbon maritime transportation requires understanding lifecycle carbon intensity (CI) of marine fuels. While well-to-tank emissions significantly contribute to total greenhouse gas emissions, many studies lack global perspective in accounting for upstream operations, transportation, refining, and distribution.
arxiv  

RNF112 Facilitates Ubiquitin‐Mediated Degradation of c‐Myc, Suppressing Proliferation, Migration and Lipid Synthesis in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
RNF112, an E3 ubiquitin ligase, is markedly reduced in bladder cancer (BLCA). It curbs BLCA cell proliferation, migration, and lipid production primarily by enhancing ubiquitin‐dependent degradation of c‐Myc. This degradation inhibits c‐Myc's role in upregulating ACLY, a crucial enzyme for lipid synthesis, highlighting RNF112's potential as a ...
Kangping Xiong   +13 more
wiley   +1 more source

Deciphering Auditory Hyperexcitability in Otogl Mutant Mice Unravels an Auditory Neuropathy Mechanism

open access: yesAdvanced Science, EarlyView.
By investigating auditory hyperexcitability in a mouse model for hereditary deafness, this study identified a subpopulation of afferent neurons of the auditory nerve marked by Otogl expression. Despite their apparently normal hearing, Otogl+/− mice display poor activation of afferent neurons processing loud sounds and an elevation of the middle the ear
Mathilde Gagliardini   +24 more
wiley   +1 more source

Study of Soil Pollution with Heavy Metals due to Leakage of Petroleum Hydrocarbons at Kermanshah Refinery [PDF]

open access: yesمحیط زیست و مهندسی آب, 2017
In recent decades, soil pollution with petroleum hydrocarbons in oil-rich countries (such as Iran) has been one of the most challenging issues. In these countries with petroleum industries, mines of oil exploration, refineries, etc., leakage from tanks ...
Ramin Sarikhani   +3 more
doaj  

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