Results 31 to 40 of about 362,607 (307)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The Quality Improvement of Grain Sampling and Inspection: Realistic Dilemma and Strategy Choice

Liang you shipin ke-ji
Grain sampling and inspection is the key process for food safety and the important technical support for the grain quality supervision. There are still many gaps between the current grain sample inspection quality and enterprise expectations.
SONG Xiao-jie, HOU Yan, LI Chun-hua, AN Chun-mei, XIE Gang   +4 more
doaj   +1 more source

Development and Its Prospect of Grain Processing Field in Academy of National Food and Strategic Reserves Administration in the Last 30 Years

Liang you shipin ke-ji, 2023
On the occasion of the 30th anniversary for the publication of “Science and Technology of Cereals, oils and Foods”, the development and achievements in the field of grain processing of the Academy of National Food and Strategic Reserves Administration ...
TAN Bin, ZHAI Xiao-tong
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Fungal Diversity of Traditional Oats Tianpei and the Fermentation Effects of Rhizopus Oryzae on Tianpei Properties

Liang you shipin ke-ji
The fungal diversity of five sweet fermented oats samples in China was studied by Illumina sequencing. The results showed that the abundance of Mucoromycota and Ascomycota peaked in the oats Tianpei samples, and a bit Basidiomycota were also included. As
REN Fei, LI Wen-yi, CHEN Shu, LIU Ming, TAN Bin   +4 more
doaj   +1 more source

Research and Prospect on Quality Evaluation Standards of Oilseeds and Oils in China

Liang you shipin ke-ji, 2023
The team of oil chemistry and processing technology from Academy of National Food and Strategic Reserves Administration (Academy of NFSRA) has made great contributions to the research and establishment of the quality evaluation standard for main oilseeds
DUAN Zhang-qun, XYE Ya-lin
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Microbial Community Succession and Nutrient Changes During the Fermentation Process of Sweet Fermented Oats by Pediococcus pentosaceus

Liang you shipin ke-ji
In this study, sweet fermented oats were fermented and made by Pediococcus pentosaceus. The strain was previously isolated in the lab. Illumina sequencing was employed to analyze the succession of microbial communities and changes throughout the ...
REN Fei, CHEN Shu, LIU Ming, LIU Yan-xiang, TAN Bin   +4 more
doaj   +1 more source

Analysis of Polychlorinated Biphenyls and Polybrominated Biphenyl Ethers in Rice and Their Risk Assessment

Liang you shipin ke-ji, 2023
The risk of polychlorinated biphenyls (PCBs) and polybrominated biphenyl ethers (PBDEs) in 45 rice samples was assessed. The rice samples were collected and ground, and all ground samples were treated according to the direct extraction-acidic silica ...
ZHANG Wei, YANG Yong-tan
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source