Results 41 to 50 of about 449,486 (309)

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

The Effect of Oil Revenue Shocks on Government Expenditure and Liquidity in Iran Economy [PDF]

Pizhūhishnāmah-i Iqtiṣād-i Inirzhī-i Īrān, 2013
Oil revenue can play an important role in the economy of Iran. Oil revenues are the main source of government expenditure and exports. On average about 60 percent of government revenue and about 80 percent of Iran’s export income comes from oil and gas ...
hosein mohammdi, amin barat zade
doaj  

The legal implications of gas flaring on climate change in Nigeria [PDF]

, 2014
Global atmospheric concentration of substances that trap heat causing warming and change of climate is caused mostly by man’s activities- anthropogenic. Since efforts to curtail anthropogenic climate change commenced and countries came together to agree ...
Oluduro, Olubisi Friday
core   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Astrocyte Enrichment of 3D Cortical Constructs Enhances Brain Repair

Advanced Science, EarlyView.
This study highlights the role of astrocytes in supporting neural progenitor cell survival and differentiation after traumatic brain injury. Astrocytes enhanced neuronal differentiation, improved cell survival in co‐cultures, and promoted integration of microfluidics‐based implants with host tissue following implantation. Additionally, increased axonal
Elisa M. Cruz, Luana C. Soares, Gretchen Greene, Fernando Messore, Mohammed Abuelem, Mingyu Li, Caroline Andersen, Mirriam Domocos, Elisa Vitiello, Rabeah Abdul Razak, Marlene Lawston, Gabriel Moser, Talia Vasaturo‐Kolodner, Mona Barkat, Roslyn M. Bill, Edward Mann, Linna Zhou, Mootaz M. Salman, Hagan Bayley, Zoltán Molnár, Francis G. Szele   +20 more
wiley   +1 more source

Evaluation of Nigeria’s Economic Diversification 1980-2023 [PDF]

International Journal of Management, Accounting and Economics
Crude oil extraction continues to be the primary economic activity in Nigeria, overshadowing other sectors and hindering the country's overall economic development.
Jide Ogunlade
doaj   +1 more source

Oil Revenue Assignments: Country Experiences and Issues

IMF Working Papers, 2002
Based on country experiences, the paper assesses policy options to assign oil revenues to subnational governments (SNGs). The literature recommends that oil revenues be centralized. Given political economy considerations, this paper suggests that a possible alternative is to assign stable oil-tax bases to oil-producing SNGs, supplementing these with ...
Eric Mottu, Ehtisham Ahmad
openaire   +2 more sources

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

One Hundred Years of Oil Income and the Iranian Economy: A Curse or a Blessing [PDF]

, 2012
This paper examines the impact of oil revenues on the Iranian economy over the past hundred years, spanning the period 1908-2010. It is shown that although oil has been produced in Iran over a very long period, its importance in the Iranian economy was ...
Mohaddes, Kamiar, Pesaran, M. Hashem
core   +6 more sources

INCOME OVER FEED COST DAN R-C RATIO USAHA TERNAK SAPI MELALUI PEMANFAATAN LIMBAH KELAPA SAWIT

Jurnal Ilmiah Peternakan Terpadu, 2017
Based on the palm oil plantation growth, Indonesia has very high potential to increase by product of palm oil through the implementation of adapted and liable technology. The research was conducted to study the ability of by product of palm
Zakiatulyaqin, I. Suswanto, R.B. Lestari, D. Setiawan, A.M.S. Munir   +4 more
doaj   +1 more source