Results 31 to 40 of about 2,666 (255)
Molecules, 2021 Essential oils (EOs) are known to have varying degrees of antimicrobial properties that are mainly due to the presence of bioactive compounds. These include antiviral, nematicidal, antifungal, insecticidal and antioxidant properties.
Aswir Abd Rashed +3 more
doaj +1 more source
INFLUENCE OF -CYCLODEXTRIN ON THE NYSTATIN RELEASE FROM OINTMENTS AND ITS ANTIFUNGAL EFFECT [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 1994 Thesolid complex of nystatin-g-cyclodextrin (g-CD) in a molar ratio 1:1 was prepared. Physico-chemical characteristics of the nystatin-g-CD) complex was studied by x-ray diffraction, differential scanning calorimetry and infrared spectroscopy. Absorption
Ehsan Elsabour +2 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman +9 more
wiley +1 more source
Фармация и фармакология (Пятигорск), 2015 There are data about positive effects from treatment of different skin diseases, sluggishly granulating wounds, and trophic ulcers with drugs based on Schizandra chinensis in literature sources.
M. S. Makieva, Yu. A. Morozov
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko +5 more
wiley +1 more source
Development and Characterization of Econazole Topical Gel
Gels, 2023 The purpose of this work was to develop a novel topical formulation of econazole nitrate based on gel that can be easily scaled up in one pot for the potential treatment of fungal and yeast infections.
Mohammad F. Bayan +2 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
BIOPHARMACEUTICAL STUDIES ON AUXILIARY COMPONENTS CHOICE FOR A GEL WITH RHAPONTICUM EXTRACT
Фармация и фармакология (Пятигорск), 2015 The development of medical compositions with herbal drug raw materials is an urgent issue of today. The production technology offered considers the use of domestic raw materials and maximal extraction of accessory agents from them, i.e.
A. A. Kostina
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source