Results 1 to 10 of about 184,823 (89)

Machine Learning Predicts the Presence of 2,4,6-Trinitrotoluene in Sediments of a Baltic Sea Munitions Dumpsite Using Microbial Community Compositions

open access: yesFrontiers in Microbiology, 2021
Bacteria are ubiquitous and live in complex microbial communities. Due to differences in physiological properties and niche preferences among community members, microbial communities respond in specific ways to environmental drivers, potentially ...
René Janßen   +10 more
doaj   +1 more source

Chromium Cycling in Redox‐Stratified Basins Challenges δ53Cr Paleoredox Proxy Applications

open access: yesGeophysical Research Letters, 2022
Chromium stable isotope composition (δ53Cr) is a promising tracer for redox conditions throughout Earth's history; however, the geochemical controls of δ53Cr have not been assessed in modern redox‐stratified basins.
David J. Janssen   +10 more
doaj   +1 more source

Hypertension is a conditional factor for the development of cardiac hypertrophy in type 2 diabetic mice. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND: Type 2 diabetes is frequently associated with co-morbidities, including hypertension. Here we investigated if hypertension is a critical factor in myocardial remodeling and the development of cardiac dysfunction in type 2 diabetic db/db mice.
Marc van Bilsen   +9 more
doaj   +1 more source

A common statement on anthropogenic hybridization of the European wildcat (Felis silvestris)

open access: yesFrontiers in Ecology and Evolution, 2023
Preserving natural genetic diversity and ecological function of wild species is a central goal in conservation biology. As such, anthropogenic hybridization is considered a threat to wild populations, as it can lead to changes in the genetic makeup of ...
Beatrice Nussberger   +53 more
doaj   +1 more source

Clinical, genetic, epidemiologic, evolutionary, and functional delineation of TSPEAR-related autosomal recessive ectodermal dysplasia 14

open access: yesHGG Advances, 2023
Summary: TSPEAR variants cause autosomal recessive ectodermal dysplasia (ARED) 14. The function of TSPEAR is unknown. The clinical features, the mutation spectrum, and the underlying mechanisms of ARED14 are poorly understood. Combining data from new and
Adam Jackson   +291 more
doaj   +1 more source

Highly efficient gene inactivation by adenoviral CRISPR/Cas9 in human primary cells.

open access: yesPLoS ONE, 2017
Phenotypic assays using human primary cells are highly valuable tools for target discovery and validation in drug discovery. Expression knockdown (KD) of such targets in these assays allows the investigation of their role in models of disease processes ...
Olaf Voets   +8 more
doaj   +1 more source

Structured game-related group therapy for an adolescent with Acquired Brain Injury: A case report

open access: yesJournal of Pediatric Rehabilitation Medicine, 2012
The use of Interactive Computer Play (ICP) in rehabilitation is developing rapidly and is especially promising in interdisciplinary pediatric rehabilitation.
Joep Janssen   +4 more
doaj   +1 more source

Association between markers of malnutrition and surgical outcomes in patients with long bone metastases: a systematic review

open access: yesJournal of Orthopaedic Reports
Background: Malnutrition affects up to 80% of patients with advanced cancer and is associated with reduced survival. However, its role in patients with long bone metastases, a growing and complex oncologic population, remains understudied.
Olaf N. van de Langerijt   +8 more
doaj   +1 more source

Intensive home treatment compared to inpatient psychiatric treatment: a 36-month follow-up of a propensity-score matched retrospective multicenter cohort study

open access: yesBMC Psychiatry
Background Intensive Home Treatment (IHT) has been implemented as an alternative to inpatient psychiatric treatment for selected patients requiring acute care. While short-term reductions in inpatient utilization have been reported, evidence on long-term
Konstantinos Nikolaidis   +6 more
doaj   +1 more source

Structured care after a DSD diagnosis in childhood: a mixed methods evaluation of the Empower-DSD program

open access: yesFrontiers in Pediatrics
IntroductionDifferences of sex development (DSD) encompass several rare diagnoses with medical and social implications. If a child is suspected of having DSD, timely and comprehensive information to the family is crucial for an undisturbed parent-child ...
Katja Wechsung   +16 more
doaj   +1 more source

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