Results 51 to 60 of about 636,994 (304)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

A new method for the identification of old-growth trees in National Forest Inventories: Application to Pinus halepensis Mill. stands in Spain [PDF]

, 2013
Old-growth trees play a very important role in the maintenance of biodiversity in forests. However, no clear definition is yet available to help identify them since tree age is usually not recorded in National Forest Inventories.
Alberdi Asensio, Iciar, Cañellas, Isabel, Condes Ruiz, Sonia, Hernández, Laura   +3 more
core   +5 more sources

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Markedly Divergent Tree Assemblage Responses to Tropical Forest Loss and Fragmentation across a Strong Seasonality Gradient [PDF]

, 2015
We examine the effects of forest fragmentation on the structure and composition of tree assemblages within three seasonal and aseasonal forest types of southern Brazil, including evergreen, Araucaria, and deciduous forests.
AR Ruschel, AT Oliveira-Filho, B Rambo, BA Santos, BMJ Engelbrecht, Carlos A. Peres, CD Inácio, CJ Krebs, D Faria, D Lobo, DE Prado, DH Janzen, Dusan Gomory, E Nimer, EE Santo-Silva, F Michalski, FA Bazzaz, FA Bazzaz, FP Werneck, FPL Melo, FPL Melo, FPL Melo, G Castillo-Campos, G Halffter, Gabriel Mendes, Giehl EL Hettwer, H Behling, H Behling, H Lorenzi, HK Gibbs, HP Veloso, J Chave, J Chave, JA Foley, JB Wilson, JL Waechter, JMC Silva, João A. Jarenkow, KE Stoner, LDS Duarte, LdS Duarte, M Benchimol, M Dufrene, M Quesada, M Sobral, M Tabarelli, M Tabarelli, M Tabarelli, M Tabarelli, MA Oliveira, Marcelo Tabarelli, MB Carlucci, MC Ribeiro, N Myers, NM Holbrook, O Hammer, PG Murphy, R Borchert, RJ Hijmans, Rodrigo L. L. Orihuela, ROJ Bierregaard, S Putz, SC Fontana, SFB Ferraz, SJ Wright, TA Gardner, TC Whitmore, TC Whitmore, van der Pijl, WF Laurance, WF Laurance, WF Laurance, WF Laurance, WF Laurance, WF Laurance, WF Laurance, WF Laurance   +76 more
core   +8 more sources

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

Advanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang, Yuchao Chen, Chuanjian Lu, Huazhen Liu, Fenglian Qin, Sisi Dai, Feifei Qiu, Haiming Chen, Weihui Lu, Jonathan S. Bromberg, Zhenhua Dai   +10 more
wiley   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

A culture of conservation: How an ancient forest plantation turned into an old‐growth forest reserve – The story of the Wamulin forest

People and Nature, 2021
The global expansion of forest plantations at the expense of natural forests, especially old‐growth forests, raises concerns about habitat loss and a decline in ecosystem services.
Zhi‐jie Yang, Qun‐rui Zheng, Ming‐xiu Zhuo, Hong‐da Zeng, James Aaron Hogan, Teng‐Chiu Lin   +5 more
doaj   +1 more source

Humidity Graph of Saddleback Biotic Succession [PDF]

, 1961
This document reflects the succession of growth in the Saddleback research station. The old forest, it shows, was eventually replaced by stages of regrowth after logging, but never fully ...
Dirks-Edmunds, Jane Claire
core   +1 more source

Increasing biomass in Amazonian forest plots [PDF]

, 2004
A previous study by Phillips et al. of changes in the biomass of permanent sample plots in Amazonian forests was used to infer the presence of a regional carbon sink.
Abel Monteagudo, Anthony Di Fiore, David A. Neill, J. Natalino M. Silva, Luzmila Arroyo, Malhi Y., Nigel C. A. Pitman, Niro Higuchi, O. L. Phillips, Oliver L. Phillips, Percy Núñez Vargas, Rodolfo Vásquez Martínez, Samuel Almeida, Simon L. Lewis, Susan G. Laurance, Terry Erwin, Timothy J. Killeen, Timothy R. Baker, William F. Laurance, Y. Malhi, Yadvinder Malhi   +20 more
core   +4 more sources

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

Advanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun, Peng‐Yi Huang, Zhi‐Ruo Zhang, Cong‐Fen Gao, Subba Reddy Palli, Shun‐Fan Wu   +5 more
wiley   +1 more source