Results 61 to 70 of about 955,969 (257)

Dentition and Life History of a 16-year-old Known-age Free-living Male Lion Panthera leo (Linnaeus, 1758) from the Kruger National Park

open access: yesKoedoe: African Protected Area Conservation and Science, 1988
Wear in the dentition of a known-age, free-living, 16-year-old male lion is described and compared to existing age-determination techniques. Aspects of his life history are described as they are in some contrast to what is known of male lions' life ...
I.J. Whyte, G.L. Smuts
doaj  

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler   +20 more
wiley   +1 more source

Use of the Knee Injury and Osteoarthritis Outcomes Survey (KOOS) in a Normal US Population

open access: yesOrthopaedic Journal of Sports Medicine, 2016
Objectives: Patient-reported outcome instruments are frequently used for assessing clinical outcomes after injury and surgery. Previously reported normative data for the Knee Injury and Osteoarthritis Outcome Survey (KOOS) instrument is limited to a ...
Robby Singh Sikka MD   +3 more
doaj   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel   +8 more
wiley   +1 more source

The body mass index and the risk of ectopic pregnancy: a 5-year retrospective case-control study

open access: yesBMC Pregnancy and Childbirth
Purpose Acknowledging the associated risk factors may have a positive impact on reducing the incidence of ectopic pregnancy (EP). In recent years, body mass index (BMI) has been mentioned in research.
Jin-Shuang Ji   +8 more
doaj   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang   +6 more
wiley   +1 more source

The experience of feeling old after a fragility fracture

open access: yesBMC Geriatrics
Background There has been little exploration of the effect of fragility fractures on patient perceptions of their age. The common assumption is that fractures “happen to old people”.
Joanna E.M. Sale   +7 more
doaj   +1 more source

Spindle Cell Carcinoma of the hypopharynx: a case report

open access: yesJournal of College of Medical Sciences-Nepal, 2018
Spindle cell carcinoma of hpopharynx is a rare pathology. It is a poorly differentiated variant of squamous cell carcinoma and morphologically resembles sarcoma. This is a disease of old age. It is usually associated with smoking and alcohol abuse.
Dillu Ram Kandel
doaj   +1 more source

The developmental history of mental disorder in old age [PDF]

open access: yesPsychiatric Bulletin, 1988
A worldwide demographic shift towards old age is being accompanied by a corresponding increase in the number of old people presenting with psychiatric disorders, and traditional systems are unable to cope with the problem.
openaire   +1 more source

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