Results 141 to 150 of about 1,318 (189)

A network pharmacology guided mechanism of action study on Oldenlandia diffusa against osteosarcoma

Letters in Drug Design & Discovery, 2022
Osteosarcoma (OS) is the most prevalent primary bone sarcoma in the global child and young adult population, and the current mainstream treatment regimens are not very effective. The unique efficacy of traditional Chinese medicine (TCM) for cancers has
Yun Yang, Jun Zhao, Liang Dong, J. Wang, B. Pan   +4 more
semanticscholar   +1 more source

Ethnopharmacology, phytochemistry and a new chemotaxonomic marker in Oldenlandia affinis (Roem. & Schult.) DC. Rubiaceae

Physical Sciences Reviews, 2022
The proper documentation of ethnopharmacological application of widely used indigenous plants and their phytochemical analysis has positively impacted the drug discovery pipeline.
F. Attah, Augustine E. Mbanu, Uche M Chukwudulue, Ugochukwu J. Jonah, N. S. Njinga   +4 more
semanticscholar   +1 more source

Cyclotides are a component of the innate defense of Oldenlandia affinis

Peptide Science, 2010
AbstractCyclotides are small cysteine‐rich plant peptides similar in size and processing to the defensins. Long‐term growth of the Rubiaceae family plant Oldenlandia affinis under different conditions reveals a diverse cyclotide gene and peptide expression profile, including tissue specificity, suggesting that different cyclotides are regulated ...
Mylne, Joshua S, Wang, Conan K, van der Weerden, Nicole L, Craik, David J   +3 more
openaire   +7 more sources

Phytochemical and Antioxidant Activity of Water and Methanol Extracts of Oldenlandia corymbosa

Journal of Basic and Social Pharmacy Research
Background: Oldenlandia corymbose is a small perennial herb used traditionally to clear toxins, activate blood circulation, and relieve urinary obstruction.
N. S. Njinga NS, F. Attah, A. Shittu, S. C. Chibueze, S. P. Oyebode, P. E. Iorkyaan, C. Mbakop, O. D. Bamidele, S. Abdullahi, O. I. Eniayewu, S. Abdulrazaq, M. David, A. Aliyu   +12 more
semanticscholar   +1 more source

Phytochemical Profiling and Pharmacognostic Evaluation of Oldenlandia corymbosa and Ocimum sanctum Leaves Hydroalcoholic Extracts: Comparative Study

Journal of Pharmaceutical Research International, 2022
Herbs are an important source of bioactive substances. These are widely used to treat several disorders for better function in the human body, minimum toxic effects, and widespread availability.
Shaktijit Das, P. Ghosh, Chandreyi Ghosh, Moumita Saha, A. Hazra, S. Chatterje   +5 more
semanticscholar   +1 more source

Allelopathic potential of Oldenlandia corymbosa and identification of its allelopathic substances

Plant Biosystems
The use of allelopathy developed as an alternative practice for weed management in agriculture. Oldenlandia corymbosa is an annual herb and notable for being applied in folk medicine.
E. H. Kyaw, K. Hossen, A. Iwasaki, Kiyotake Suenaga, H. Kato‐Noguchi   +4 more
semanticscholar   +1 more source

Abstract 7308: Induction of apoptosis via the regulation of pro-apoptotic and anti-apoptotic proteins in pancreatic adenocarcinoma BxPC-3 cells by Chinese medicinal herbs Scutellaria barbata and Oldenlandia diffusa

Cancer Research
Apoptosis is a controlled program cell death process that the body uses to combat cancer development. Pancreatic cancer is a devastating disease with a poor prognosis. It is usually symptom-free during development and is advanced at diagnosis.
Christine Choi, Sarah Wolf, Rekha Isaac, Elim Choi, Abigail Shim, Angel Campana, P. Uppala, R. Hayes, B. Y. Wong   +8 more
semanticscholar   +1 more source

[Chemical Constituents from Oldenlandia diffusa].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2018
To study the chemical constituents of water extracted fraction from Oldenlandia diffusa.The compounds were isolated and purified by column chromatography on macroporous resin,silica gel,MCI gel,Sephadex LH-20,ODS medium pressure liquid chromatography and RP-semi-preparative HPLC.
He, Ma, Fang-li, Li, Fang, Wang, Qi, Guo, Guan-shang, Cao, Pei-min, Yang   +5 more
openaire   +2 more sources

Investigating the material basis and molecular mechanisms of Oldenlandia diffusa in the treatment of papillary thyroid carcinoma: a network pharmacology and experimental study

Translational Cancer Research
Background Papillary thyroid carcinoma (PTC) is among the most prevalent forms of thyroid cancer. Traditional Chinese medicine (TCM) has been widely employed in the management of PTC, with Oldenlandia diffusa (OD) demonstrating potential in cancer ...
Chao Ding, Tie-Feng Shi, Xiang-jun Kong, Jiayun Dong, Yingming Liu, Yongsheng Zhao   +5 more
semanticscholar   +1 more source

DOSE-DEPENDENT GASTROPROTECTIVE AND IMMUNOMODULATORY EFFECTS OF Oldenlandia capitellata Kuntze LEAF EXTRACT IN AN INDOMETHACIN-INDUCED MURINE MODEL

Journal of Science and Technology - IUH
Objectives: This study aimed to evaluate the dose-response correlation between Oldenlandia capitellata Kuntze leaf extract (EE-OC) and its gastroprotective effects in an indomethacin-induced murine model, with a specific focus on the relationship between
B. H. Quân, T. T. Nhung
semanticscholar   +1 more source