Results 191 to 200 of about 2,553,189 (362)
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern+7 more
wiley +1 more source
Nutrition for the Older Adult: Diet Needn't Be Hazardous to Health
Maria Salerno
openalex +1 more source
A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla+15 more
wiley +1 more source
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert+13 more
wiley +1 more source
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf+10 more
wiley +1 more source
An Analysis of the State of Empowerment of Females vis-à-vis Males at Old Ages in India [PDF]
The problem of ageing population in the developing countries has a special gender dimension as females not only outnumber males among older adults, but also differ from their male counterparts with respect to economic status, marital status and health ...
Bakshi, Sanjeev, Pathak, Prasanta
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak+8 more
wiley +1 more source
Ageism, empathy, attitudes, and aging anxiety: an evaluation of the Gray for a Day program with college students [PDF]
Master of ScienceSchool of Family Studies and Human ServicesErin L. YellandStudies have shown ageism, empathy, attitudes toward older adults and aging anxiety to be important factors for not only individuals planning to work with older adults, but for ...
Goss, Kaylee
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