Results 221 to 230 of about 1,167,435 (311)

Barriers and facilitators of deprescribing for older adults with cancer and polypharmacy. [PDF]

J Geriatr Oncol
Agyei KG, Malhotra A, Norton SA, Mohamed M, Juba KM, Mohile S, Ramsdale E.   +6 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

COVID-19 Vaccine Effectiveness Among Older Adults.

JAMA Netw Open
Laniece Delaunay C, Mateo-Urdiales A, Pérez-Gimeno G, O'Reilly K, Uras M, Erdwiens A, Mlinaric I, Túri G, Martínez-Baz I, Meijer A, Rodrigues AP, Lazar M, Latorre-Margalef N, Lucaccioni H, Verdasca N, Bella A, Rafael de la Cruz Lopez MA, Kelly E, Enouf V, Tolksdorf K, Puzelli S, Ibáñez Pérez AC, Fitzgerald M, Masse S, Oh DY, Kaczmarek M, Bacci S, Kissling E, VEBIS Primary Care Vaccine Effectiveness Group.   +28 more
europepmc   +1 more source

Association of Combined Lifestyle Behaviors With Healthspan in Older Adults. [PDF]

J Am Geriatr Soc
Robb C, Carr PR, Ball J, Polekhina G, Clayton-Chubb D, George ES, Fitzpatrick J, Beilin LJ, Newman AB, Owen A, Orchard SG, Tran C, Ryan J, McNeil JJ.   +13 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Socioeconomic differences in older adults' intention to use mhealth applications. [PDF]

BMC Geriatr
van Elburg F, Nieboer AP, Askari M.
europepmc   +1 more source

Falls in older adults

Canadian Medical Association Journal
Lafleur, Benoit, Montero-Odasso, Manuel, Huang, Shirley   +2 more
openaire   +2 more sources

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Statin use and cognitive outcomes in older adults. [PDF]

Am J Prev Cardiol
Rossi R, Rahman MM, Akman Z, Moreines LT, Nouri A, Mouslmani MA, Ezenna C, Stoehr KA, Nezhad SA, Wang SY, Damluji AA, Nanna MG.   +11 more
europepmc   +1 more source