Results 251 to 260 of about 9,549,043 (343)

Co-Designing a Digital Solution for Decreasing Loneliness and Social Isolation Among Older People in Sweden: Explorative Study (Preprint)

Caroline Eklund, Viktoria Zander, Annelie K. Gusdal, Charlotta Åkerlind, Petra von Heideken Wågert   +4 more
openalex   +1 more source

A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

Advanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra, Fleur R. Semmekrot, Nuno Araújo‐Gomes, Daniël Wijnperle, Monique M. A. Helsen, Martijn H.J. Van Den Bosch, Loes. I. Segerink, Séverine Le Gac, Marcel Karperien   +8 more
wiley   +1 more source

An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy

Advanced Healthcare Materials, EarlyView.
A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou, Chaoyang Huang, Yanqi Chen, Tingzi Zhao, Fengyi Zhu, Gong Jun, Jinrong Zhang, Yingsong Pan, Qiulan Wen, Lei Yang, Huihui Zhang, Lianglong Chen   +11 more
wiley   +1 more source

A Pseudo‐Mytilus Edulis Foot Protein‐Based Hydrogel Adhesive with Osteo‐Vascular‐Immune Coupling Effects for Osteoporotic Bone‐Implant Integration

Advanced Materials, EarlyView.
Inspired by mussel proteins, YDC‐Gel‐Zn is a smart bone glue designed for osteoporotic implants. It adheres strongly to both metal implants and bone for initial fixation. In osteoporosis's inflammatory environment, it sequentially releases zinc ions and therapeutic peptides: the zinc modulates immune cells to reduce inflammation, while the peptides ...
Wentao Wang, Zhenyu Li, Siming Zhang, Yue Ma, Lei Yu, Qidong Zhang, Guoqing Pan, Dechun Geng, Chen Zhu, Jiaxiang Bai   +9 more
wiley   +1 more source

A study of the relationship between mutual aid and the mental health of older people. [PDF]

BMC Public Health
Liu X, Zheng L, Li M, Hu B.
europepmc   +1 more source

Archeo‐Inspiration from the Cultural History of Glass: Historic Accounts, Anecdotes and Hard Facts as Challenges to Modern Material Science

Advanced Materials, EarlyView.
Glass, historically valued for its purity and durability, has long inspired artists and societies. This article introduces the concept of “Archeo‐Inspiration”, drawing on cultural and historical contexts of glass to guide future material innovations.
Eva von Contzen, Julia von Ditfurth, Fabian Stroth, Bastian E. Rapp   +3 more
wiley   +1 more source

Perceived rehabilitation needs of older people with dementia : A qualitative interview study. [PDF]

BMC Geriatr
Mäenpää O, Edgren J, Aaltonen M, van Aerschot L, Pirhonen J, Kulmala J.   +5 more
europepmc   +1 more source

A Wearable, Dual Closed‐loop Insulin Delivery System for Precision Diabetes Management

Advanced Materials, EarlyView.
A wearable dual closed‐loop drug delivery system for diabetes management is presented, featuring an adaptive, on‐body trained edge AI algorithm for precise insulin delivery, which enhances therapeutic accuracy from 92.10% to 98.82%. Abstract Effective blood glucose management is an increasing demand worldwide.
Xuecheng He, Wei Huang, Wensheng Lin, Binbin Cui, Xinyu Tian, Jing Bai, Dingyao Liu, Ivo Pang, Hao Huang, Shixian Lin, Jixiang Zhu, Jinqiang Wang, Shiming Zhang   +12 more
wiley   +1 more source

Piezoelectric Stimulation of Neural Cells: Exploring the Synergistic Potential of Hybrid Scaffolds for Enhanced Regeneration

Advanced Materials Interfaces, EarlyView.
Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton, Chris R. Bowen, Hamideh Khanbareh   +2 more
wiley   +1 more source