Results 51 to 60 of about 11,669,963 (401)

Long-Term Care for Older People

When We're Sixty-Four: Opportunities and Challenges for Public Policies in a Population-Aging Context in Latin America, 2020
Population ageing is a global reality. So is the fact that, as people age, they tend to require greater care and assistance in activities related to daily living. Nevertheless, current debates about long-term care for older persons are remarkably narrow.
Rafael P. Rofman, I. Apella
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Emergency Preparedness for Older People [PDF]

, 2003
After the 9/11 World Trade Center attacks, a large population of older persona and people with disabilities living near the disaster area were left stranded in their homes without assistance.
Nora O'Brien
core  

Long-term health conditions and their impact on people with sleep disturbances and dementia

BMC Geriatrics
Background Sleep disturbances are common for people with dementia and can be distressing for them and their family. People with dementia live with an average of five other long-term conditions (LTCs).
Penny Rapaport, Ankita Bhojwani, Lucy Webster, Sarah Amador, Malvika Muralidhar, Gill Livingston   +5 more
doaj   +1 more source

The influence of ACE inhibitors and ARBs on hospital length of stay and survival in people with COVID-19

International Journal of Cardiology: Heart & Vasculature, 2020
Objective: During the COVID-19 pandemic the continuation or cessation of angiotensin-converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARBs) has been contentious.
Philip Braude, Ben Carter, Roxanna Short, Arturo Vilches-Moraga, Alessia Verduri, Lyndsay Pearce, Angeline Price, Terence J. Quinn, Michael Stechman, Jemima Collins, Eilidh Bruce, Alice Einarsson, Frances Rickard, Emma Mitchell, Mark Holloway, James Hesford, Fenella Barlow-Pay, Enrico Clini, Phyo Kyaw Myint, Susan Moug, Kathryn McCarthy, Jonathan Hewitt   +21 more
doaj   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Audit and group feedback in nursing home physician groups: lessons learned from a qualitative study

BMC Health Services Research
Background Audit and group feedback (A&F) is an instrument used to encourage healthcare professionals to improve the quality of care. Clinical practice was audited against a set of criteria and fed back to a group by a facilitator.
Gary Y. C. Yeung, Charlotte A. W. Albers, Martin Smalbrugge, Martine C. de Bruijne, Patricia Jepma, Karlijn J. Joling   +5 more
doaj   +1 more source

Wessex Acute Frailty Audit: applying quality improvement methodology to design and implement a regional frailty audit using a collaborative, multiprofessional approach

BMJ Open Quality, 2020
Introduction An acute hospital stay increases the risk of negative outcomes for those living with frailty. This paper describes the application of quality improvement methodology to design and implement a regional audit to gain an understanding of care ...
Teresa Corbett, Kathy Wallis, Cheryl Davies, Lucy Anne Lewis, Kerry Burrows, Claire Spice   +5 more
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Prescribing for older people [PDF]

BMJ, 2008
#### Summary points About a fifth of the population in the United Kingdom is 60 years or older,1 yet people in this age group receive 59% of dispensed prescriptions and account for more than half of NHS drug costs.2 Older people often have several coexisting medical problems and take multiple drugs.
James C Milton, Ian Hill-Smith, Stephen D. Jackson   +2 more
openaire   +3 more sources