Results 71 to 80 of about 12,523,126 (342)

Risk of venous thrombosis and pulmonary embolism in older in-patients with mental illness: systematic review

BJPsych Bulletin
Aims and method Venous thromboembolism (VTE) is a fatal condition affecting older people. This study aims to identify specific risk factors for VTE in older psychiatric in-patients within mental hospital settings.
Damodar Chari, Tamara Chithiramohan, Ina Sawhney, Elizabeta B. Mukaetova-Ladinska, Lucy Beishon, Hari Subramaniam   +5 more
doaj   +1 more source

The influence of ACE inhibitors and ARBs on hospital length of stay and survival in people with COVID-19

International Journal of Cardiology: Heart & Vasculature, 2020
Objective: During the COVID-19 pandemic the continuation or cessation of angiotensin-converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARBs) has been contentious.
Philip Braude, Ben Carter, Roxanna Short, Arturo Vilches-Moraga, Alessia Verduri, Lyndsay Pearce, Angeline Price, Terence J. Quinn, Michael Stechman, Jemima Collins, Eilidh Bruce, Alice Einarsson, Frances Rickard, Emma Mitchell, Mark Holloway, James Hesford, Fenella Barlow-Pay, Enrico Clini, Phyo Kyaw Myint, Susan Moug, Kathryn McCarthy, Jonathan Hewitt   +21 more
doaj   +1 more source

Interventions for preventing falls in older people in care facilities and hospitals

Cochrane Database of Systematic Reviews, 2018
Background Falls in care facilities and hospitals are common events that cause considerable morbidity and mortality for older people. This is an update of a review first published in 2010 and updated in 2012.
I. Cameron, S. Dyer, Claire E Panagoda, G. Murray, K. Hill, Robert G Cumming, N. Kerse   +6 more
semanticscholar   +1 more source

A Multidimensional Approach to Frailty in Older People.

Ageing Research Reviews, 2020
Frailty is an important factor determining a higher risk of adverse health outcomes in older adults. Although scientific community in the last two decades put a lot of effort for its definition, to date no consensus was reached on its assessment.
A. Pilotto, C. Custodero, S. Maggi, M. Polidori, N. Veronese, L. Ferrucci   +5 more
semanticscholar   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Giant Primary Cutaneous Nodular Melanoma of the Forehead: A Case Report

Geriatrics
Background: The incidence of melanoma is increasing globally. The estimated worldwide incidence is projected to increase from 324,635 cases in 2020 to 510,000 in 2040. In the UK, melanoma accounts for 4% of all new cases of cancer. Melanomas occurring in
Samantha Montandon, Charles Jefferson-Loveday, Matthew Sommerlad, Harnish P. Patel   +3 more
doaj   +1 more source

Wessex Acute Frailty Audit: applying quality improvement methodology to design and implement a regional frailty audit using a collaborative, multiprofessional approach

BMJ Open Quality, 2020
Introduction An acute hospital stay increases the risk of negative outcomes for those living with frailty. This paper describes the application of quality improvement methodology to design and implement a regional audit to gain an understanding of care ...
Teresa Corbett, Kathy Wallis, Cheryl Davies, Lucy Anne Lewis, Kerry Burrows, Claire Spice   +5 more
doaj   +1 more source

Older people and research partnerships [PDF]

, 2003
Increasing consumer consultation is a priority for those involved in health and social care research and practice, with promoting greater public participation being widely accepted as 'a good thing' (Reason, 1994: 3).
Baxter L, Department of Health, Department of Health, Department of Health, Department of Health, Executive, Executive Trent, Reason P, Tetley J, Whitmore E   +9 more
core   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Establishing the core elements of a frailty at the front door model of care using a modified real-time Delphi technique

BMC Emergency Medicine, 2023
Background Innovations in models of care for older adults living with frailty presenting to the emergency department (ED) have become a key priority for clinicians, researchers and policymakers due to the deleterious outcomes older adults experience due ...
Íde O’Shaughnessy, Christine Fitzgerald, Aoife Whiston, Patrick Harnett, Helen Whitty, Des Mulligan, Marian Mullaney, Catherine Devaney, Deirdre Lang, Jennifer Hardimann, Brian Condon, Christina Hayes, Alison Holmes, Louise Barry, Claire McCormack, Megan Bounds, Katie Robinson, Margaret O’Connor, Damien Ryan, Denys Shchetkovsky, Fiona Steed, Leonora Carey, Emer Ahern, Rose Galvin   +23 more
doaj   +1 more source