Results 81 to 90 of about 12,523,126 (342)

Adverse reactions of amiodarone [PDF]

, 2019
Adverse drug reaction is defined by the World Health Organization as any response to a drug that is noxious and unintended and occurs at a dose normally used in man.
Calvosa, Leonardo, Ciacciarelli, Marco, Colunga Biancatelli, Ruben Ml, Congedo, Viviana, Iuliano, Luigi, Polidoro, Alessandro   +5 more
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Cost-effectiveness and return-on-investment of C-reactive protein point-of-care testing in comparison with usual care to reduce antibiotic prescribing for lower respiratory tract infections in nursing homes: a cluster randomised trial

BMJ Open, 2022
Objectives C-reactive protein point-of-care testing (CRP POCT) is a promising diagnostic tool to guide antibiotic prescribing for lower respiratory tract infections (LRTI) in nursing home residents.
Maurits W van Tulder, Cees M P M Hertogh, Judith E Bosmans, Theo J M Verheij, Rogier M Hopstaken, Mohamed El Alili, Tjarda M Boere, Laura W van Buul   +7 more
doaj   +1 more source

Interventions to reduce social isolation and loneliness among older people: an integrative review

Health and Social Care in the community, 2018
Loneliness and social isolation are major problems for older adults. Interventions and activities aimed at reducing social isolation and loneliness are widely advocated as a solution to this growing problem.
C. Gardiner, G. Geldenhuys, M. Gott
semanticscholar   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Home-based geriatric rehabilitation after inpatient rehabilitation: a redesign and feasibility study

BMC Geriatrics
Background There is a shift from inpatient to home-based geriatric rehabilitation (HBGR), and potential benefits are demonstrated. Previously, a theoretical HBGR model, version 1.0, has been developed, outlining its essential components.
Astrid D. Preitschopf, Margriet Pol, Bianca Buurman, Marije Holstege   +3 more
doaj   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Randomized crossover trial of a modified ketogenic diet in Alzheimer’s disease

Alzheimer’s Research & Therapy, 2021
Background Brain energy metabolism is impaired in Alzheimer’s disease (AD), which may be mitigated by a ketogenic diet. We conducted a randomized crossover trial to determine whether a 12-week modified ketogenic diet improved cognition, daily function ...
Matthew C. L. Phillips, Laura M. Deprez, Grace M. N. Mortimer, Deborah K. J. Murtagh, Stacey McCoy, Ruth Mylchreest, Linda J. Gilbertson, Karen M. Clark, Patricia V. Simpson, Eileen J. McManus, Jee-Eun Oh, Satish Yadavaraj, Vanessa M. King, Avinesh Pillai, Beatriz Romero-Ferrando, Martijn Brinkhuis, Bronwyn M. Copeland, Shah Samad, Shenyang Liao, Jan A. C. Schepel   +19 more
doaj   +1 more source

Transitions between frailty states among community-dwelling older people: A systematic review and meta-analysis.

Ageing Research Reviews, 2019
Frailty is a well-established risk factor for adverse health outcomes. However, comparatively little is known about the dynamic nature of frailty and the extent to which it can improve. The purposes of this study were to systematically search for studies
G. Kojima, Y. Taniguchi, S. Iliffe, S. Jivraj, K. Walters   +4 more
semanticscholar   +1 more source

An investigation of factors associated with the health and well-being of HIV-infected or HIV-affected older people in rural South Africa [PDF]

, 2012
BackgroundDespite the severe impact of HIV in sub-Saharan Africa, the health of older people aged 50+ is often overlooked owing to the dearth of data on the direct and indirect effects of HIV on older people's health status and well-being.
A Razzaque, AJ Herbst, B Curtis, BB Reeve, BB Reeve, BM Mayosi, C Ardington, C Debpuur, C Kyobutungi, C Wallrauch, CF Houlihan, D Posel, DW Wang, E Duflo, E Wouters, EJ Schatz, F Scholten, F Tanser, F Xavier Gomez-Olive, G Louwagie, GH Ice, H Boon, H Van Minh, H Van Minh, J Burns, J Joubert, Jane Falkingham, K Kahn, K Kahn, K Kinsella, K Peltzer, L Gilbert, LC Hamilton, LR Fairall, M Nyirenda, M Wilson, MA Mwanyangala, Makandwe Nyirenda, Maria Evandrou, Marie-Louise Newell, MS Westaway, N Ng, N Nguyen, NA Cooperman, P Kowal, P Moen, Paul Kowal, PC Mutevedzi, Portia Mutevedzi, R Benitha, R Ssengonzi, R Ssengonzi, S Dougan, S Hirve, S Jitapunkul, SM Tollman, Somnath Chatterji, SR Kimuna, StataCorp, StataCorp, TA Moultrie, TA Moultrie, United Nations, V Hosegood, V Hosegood, V Hosegood, Victoria Hosegood, W Muhwava, WHO, WHO: ICD-10, WHOQoL Group, Z Zimmer, Z Zimmer   +72 more
core   +2 more sources