Results 31 to 40 of about 13,548,594 (226)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Older People's Commissioner for Wales - Annual Review 08/09 putting older people at our heart

open access: yes, 2009
The role of Older People\u27s Commissioner for Wales was created with a range of powers to help improve the lives of older people in Wales. This is the first Commission of its kind.
Older People, Health service
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

National Council on Ageing and Older People annual report, 1998. [PDF]

open access: yes, 1999
In 1998 the Council continued to fulfil its core functions in relation to the commissioning and publication of research into various issues affecting the lives of our older citizens.
National Council on Ageing and Older People
core  

Issues of alcohol misuse among older people : attitudes and experiences of social work practitioners [PDF]

open access: yes, 2008
This small-scale qualitative research focused on the experiences of social workers vis--vis older people who misuse alcohol. Based in an Older People's Team in the west of Scotland, the study explored service provision for alcohol misuse and examined ...
Palattiyil, George   +2 more
core   +4 more sources

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

National Council on Ageing and Older People annual report 2003 [PDF]

open access: yes, 2004
2003 was a busy and productive year for the National Council on Ageing and Older People, during which it continued to fulfil its mandate to advise the Minister for Health and Children and other Ministers on all aspects of ageing and older people in ...
National Council on Ageing and Older People
core  

How do ageism, death anxiety and ageing anxiety among medical students and residents affect their attitude towards medical care for older patients: a systematic review

open access: yesBMC Medical Education
Background Although the number of older patients requiring medical care is increasing, caring for older patients is often seen as unattractive by medical trainees (i.e., medical students, residents, interns, and fellows).
Emma J. Draper   +5 more
doaj   +1 more source

Effective health education methods to improve self-care in older people with chronic heart failure: A systematic review

open access: yesHealth Sciences Review, 2022
Objective: Health education is proven to be able to improve self-care behavior, reduce hospital readmission, hospitalization or death in the older people with chronic diseases. Strategies in delivering education can make it easier for the older people to
Sriyanti Mansyur   +3 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

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