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The mechanism of oleic acid nitration by •NO2

Free Radical Biology and Medicine, 2008
Fatty acid nitration is a recently discovered process that generates biologically active nitro lipids; however, its mechanism has not been fully characterized. For example, some structural details such as vinyl and allyl isomers of the nitro fatty acids have not been established.
John R. Falck   +5 more
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Regulation of neutrophil activation by oleic acid

Biochimica et Biophysica Acta (BBA) - General Subjects, 1994
Physiological concentrations of oleic acid inhibited C5a-induced myeloperoxidase release from neutrophils. The inhibition occurred promptly following the addition of oleic acid, was dose-dependent and saturable, and was greater at low concentrations of C5a.
Iyad I. Barghouti, Abd Al-Roof Higazi
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Toxicity of oleic acid anilide in rats

Archives of Environmental Contamination and Toxicology, 1991
In the present investigation, we have studied the toxic potential of oleic acid anilide (OAA) and heated oleic acid anilide (HOAA) in relation to the toxic oil syndrome (TOS). Male Sprague-Dawley rats were given 250 mg/kg of OAA or HOAA in mineral oil by gavage, on alternate days for 2 weeks (total 7 doses). The control rats received an equal volume of
A. Palafox   +4 more
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Oleic acid lung injury in sheep

Journal of Applied Physiology, 1986
Intravenous infusion of oleic acid into experimental animals causes acute lung injury resulting in pulmonary edema. We investigated the mechanism of oleic acid lung injury in sheep. In experiments with anesthetized and unanesthetized sheep with lung lymph fistulas, we measured pulmonary arterial and left atrial pressures, cardiac output, lung lymph ...
Michael R. Flick   +2 more
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Oleic Acid Lung Damage in Pigs

Acta Anaesthesiologica Scandinavica, 1982
With the purpose of producing a lung damage model simulating post‐traumatic pulmonary insufficiency, oleic acid 0.1 ml‐1 kg‐1 body weight (b. w.) was infused intravenously into eight mechanically ventilated young pigs, and the effects were studied for 2 h. After the infusion, Pao2 during air breathing decreased to a fairly low and stable level of about
E. Haldén, U. Hedstrand, K. Torsner
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Catalyzed esterification of oleic acid

Journal of the American Oil Chemists' Society, 1960
ConclusionsIt has been shown that the effectiveness of certain divalent metal salts as esterification catalysts can be quantitatively compared and that for the Group II B series their effectiveness is inversely proportional to their ionic volume.
J. S. Heckles, L. H. Dunlap
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Oleic acid induced pancreatitis in pigs

Journal of Surgical Research, 1991
An experimental model of edematous pancreatitis in pigs was established and measurement of pancreatic macro- and microcirculatory parameters and determinations of pancreatic enzymes (lipase, phospholipase A) and vasoactive mediators (prostanoids, kallikrein, kininogen) were performed.
B. Vollmar   +7 more
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Oleic acid desaturation in Tetrahymena pyriformis

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1983
The desaturation of oleoyl-CoA by a microsomal preparation from Tetrahymena has been studied. Desaturation of oleoyl-CoA required oxygen and NADH, and was inhibited by cyanide. HPLC analysis of fatty acid phenacyl esters, prepared from TLC-purified phospholipid, confirmed that radioactivity appeared in oleate, linoleate and gamma-linolenate.
N. Kambadur   +3 more
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Oleic acid-induced Ca2+ mobilization in human platelets: is oleic acid an intracellular messenger?

Journal of Lipid Mediators and Cell Signalling, 1997
The purpose of this study was to explore the effect of oleic acid (OA) on intracellular Ca2+ mobilization in human platelets. When applied extracellularly, OA produced a concentration dependent rise in cytosolic [Ca2+] ([Ca2+]cyt) when extracellular [Ca2+] (Ca2+]ext) was zero (presence of EGTA), suggesting that OA caused an intracellular release of Ca2+
Donald J. Hanahan   +2 more
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Oleic Acid and Inhibition of Glucosyltransferase

2010
Publisher Summary Dental caries in humans is associated primarily with the acidogenic and aciduric properties of the mutans streptococci. The colonization and accumulation of these cariogenic oral streptococci on the tooth surface have been associated with the ability of mutans streptococci to synthesize extracellular glucan from sucrose.
Hae-Ik Rhee, Shin-Geon Choi, Se-Ra Won
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